CRISPR-Cas9-modified <em>pfmdr1</em> protects <em>Plasmodium falciparum </em>asexual blood stages and gametocytes against a class of... (Publications)
Emerging resistance to first-line antimalarial combination therapies threatens malaria treatment and the global elimination campaign. Improved therapeutic strategies are required to protect existing drugs
Characterization of the small exported <em>Plasmodium falciparum</em> membrane protein SEMP1 (Publications)
Survival and virulence of the human malaria parasite Plasmodium falciparum during the blood stage of infection critically depend on extensive host cell refurbishments mediated through export of numerous
Micronutrient status, food security, anaemia, <em>Plasmodium</em> infection, and physical activity as predictors of primary schoolchildren's body... (Publications)
increased MVPA was associated with reduced fat mass among girls. CONCLUSIONS: The integration of Malaria control programs with efforts to improve household healthy diet and promote physical activity can
A path to cooperation between China and Mongolia towards the control of echinococcosis under the Belt and Road Initiative (Publications)
development goals, especially goal 3, target 3.3: by 2030, end the epidemics of AIDS, tuberculosis, malaria and neglected tropical diseases and combat hepatitis, water-borne diseases and other communicable
Key contributions by the Swiss Tropical and Public Health Institute towards new and better drugs for tropical diseases (Publications)
clonorchiasis, fascioliasis and opisthorchiasis), human African trypanosomiasis, leishmaniasis, malaria, schistosomiasis, soil-transmitted helminthiasis and tuberculosis. In this article, we show case
Chemoproteomics validates selective targeting of <em>Plasmodium</em> M1 alanyl aminopeptidase as an antimalarial strategy (Publications)
New antimalarial drug candidates that act via novel mechanisms are urgently needed to combat malaria drug resistance. Here, we describe the multi-omic chemical validation of Plasmodium M1 alanyl metal
The cost-effectiveness of permethrin impregnated bednets in preventing child mortality in Kassena-Nankana district of Northern Ghana (Publications)
bednets are now being widely promoted as an effective means of protecting African children against malaria, but there is little evidence of their cost-effectiveness. The impact on child mortality of introducing
Phase III study to compare intravenous with oral iron to treat iron deficiency anaemia (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/phase-iii-study-to-compare-intravenous-with-oral-iron-to-treat-iron-deficiency-anaemia
supply, different perception of medication needs and compliance as well as concomitant diseases like malaria, soil-transmitted helminths, schistosomiasis or HIV. All these factors may influence the efficacy
Fiona Vanobberghen (People)
https://www.swisstph.ch/en/staff/profile/people/fiona-vanobberghen
on Design and analysis of pharmacokinetic and pharmacodynamic (PK/PD) studies for helminths and malaria In addition, my experience and interests span HIV epidemiology and clinical trials, the use of marginal
Bioisosteric ferrocenyl aminoquinoline-benzimidazole hybrids: antimicrobial evaluation and mechanistic insights (Publications)
activity against the chloroquine-sensitive NF54 and multi-drug resistant K1 strains of the human malaria parasite, Plasmodium falciparum. All compounds were active against the two strains, generally showing
