Approaches to the evaluation of malaria elimination of county level: case of study in the Yangtze river delta region (Publications)
As the progress on transition from malaria control to malaria elimination in the People's Republic of China (P.R. China), four counties/districts, namely Zhabei District and Songjiang District of Shanghai [...] representatives of the Yangtze River Delta region, were included in the pilot project of the national malaria elimination programme in P.R. China. A baseline survey was conducted first. The main measures performed [...] performed were blood examination of febrile cases, improving the...
Feasibility and roadmap analysis for malaria elimination in China (Publications)
the current status of the malaria control programme at the county level in accordance with the criteria of the World Health Organisation, the gaps and feasibility of malaria elimination at the county and [...] capacity of the professional team, and the intensity of intervention. Finally, a roadmap for national malaria elimination in the People's Republic of China is proposed based on the results of a feasibility
Treatment of chloroquine-resistant malaria using pyrimethamine in combination with berberine, tetracycline or cotrimoxazole (Publications)
Two hundred and fifteen patients with chloroquine-resistant malaria were randomised into three groups. The first group of 82 patients were given pyrimethamine and berberine (berberine group), the second [...] the combination of pyrimethamine and berberine gives the best results for chloroquine resistant malaria
<em>In vitro</em> antiplasmodial screening of ethnopharmacologically selected South African plant species used for the treatment of malaria (Publications)
treatment of malaria and associated symptoms. To evaluate the in vitro antiplasmodial efficacy and cytotoxic properties of indigenous medicinal plants used by Venda people against malaria. MATERIALS AND
Heterochromatin protein 1 secures survival and transmission of malaria parasites (Publications)
variant expression of surface antigens allows the malaria parasite Plasmodium falciparum to evade immune recognition during blood stage infection and secure malaria transmission. We demonstrate that heterochromatin [...] have major implications for developing antidisease and transmission-blocking interventions against malaria.
Mosquito behavior change after distribution of bednets results in decreased protection against malaria exposure (Publications)
efficacy of vector control in reducing malaria transmission. Methods.: In this study, we quantified human exposure to both bites and infective bites of a major malaria vector in Papua New Guinea over the [...] the course of 4 years surrounding nationwide bednet distribution. We also quantified malaria infection prevalence in the human population during the same time period. Results.: We observed a shift in mosquito [...] period and was lowest in the adult population, who may be an important...
Spatial distribution of<em> Falciparum</em> malaria infections in Zanzibar: implications for focal drug administration strategies targeting... (Publications)
Background.: Optimal use of mass/targeted screen-and-treat or mass or focal drug administration as malaria elimination strategies remains unclear. We therefore studied spatial distribution of Plasmodium