Sleeping hearts: the role of the heart in sleeping sickness (human African trypanosomiasis) (Publications)
OBJECTIVES: To estimate the frequency and evolution of heart involvement in human African trypanosomiasis (HAT) using electrocardiogram (ECG) findings; to describe these findings and to assess the fre
An unusual type IB topoisomerase from African trypanosomes (Publications)
African trypanosomes are ancient eukaryotes that cause lethal disease in humans and cattle. Available drugs are inadequate and the need for new therapeutic targets is great. Trypanosoma brucei and rel
Topoisomerases in kinetoplastids (Publications)
Topoisomerases are enzymes that mediate topological changes in DNA that are essential for nucleic acid biosynthesis and for cell survival. The kinetoplastid protozoa, which include pathogenic trypanos