Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in <em>Plasmodium falciparum</em> (Publications)
The malaria parasite Plasmodium falciparum undergoes antigenic variation to evade host immune responses through switching expression of variant surface proteins encoded by the var gene family. We demo
Symptoms and transmission of intestinal cryptosporidiosis (Publications)
Cryptosporidium spp are a cause of diarrhoea in toddlers. Symptoms and routes of transmission were investigated in a prospective case-control study in the city and surroundings of Basel, Switzerland.
Field evaluation of a recombinant glutathione S-transferase-based pyrethroid quantification assay (Publications)
A recombinant glutathione S-transferase (GST)-based pyrethroid quantification assay was field-tested in Ifakara, Tanzania. Initial laboratory tests suggested that all reagents used in the assay should
Seroprevalences and local variation of human and livestock brucellosis in two villages in Gharbia Governorate, Egypt (Publications)
This study aimed at assessing the epidemiology of brucellosis among both human and livestock populations in an endemic area in Egypt. A cross-sectional survey was conducted in two villages, where 616
Okundoperoxide, a bicyclic cyclofarnesylsesquiterpene endoperoxide from <em>Scleria striatinux</em> with antiplasmodial activity (Publications)
Okundoperoxide (1) was isolated by bioassay-guided fractionation of extracts from Scleria striatinux (syn. S. striatonux). The compound contains a cyclic endoperoxide structural moiety and possesses m
Prenatal exposure to a farm environment modifies atopic sensitization at birth (Publications)
BACKGROUND: Previous cross-sectional surveys have suggested that maternal exposure to animal sheds during pregnancy exerted a protective effect on atopic sensitization in children lasting until school
Participatory mapping of target areas to enable operational larval source management to suppress malaria vector mosquitoes in Dar es Salaam, Tanzania (Publications)
ABSTRACT: BACKGROUND: Half of the population of Africa will soon live in towns and cities where it can be protected from malaria by controlling aquatic stages of mosquitoes. Rigorous but affordable an
Perimenstrual increase in bronchial hyperreactivity in premenopausal women: results from the population-based SAPALDIA 2 cohort (Publications)
BACKGROUND: Studies on perimenstrual asthma are inconsistent, and different methodologies limit comparisons. OBJECTIVE: To investigate cyclic variations in bronchial hyperreactivity (BHR) to methachol
