Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis (Publications)
PURPOSE OF REVIEW: Praziquantel (PZQ) is the only drug being used to treat human schistosomiasis on a large scale. This review focuses on current knowledge about the mechanisms of action of PZQ, prosp
Relationship of hyperactivity/inattention with adiposity and lifestyle characteristics in preschool children (Publications)
We performed a cross-sectional study in 450 nonreferred preschool children aged 4 to 6 years to assess the association between hyperactivity/inattention with adiposity and lifestyle characteristics. M
Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles (Publications)
1,2,4-Oxadiazole and 1,2,3-triazole containing heterocyclic compounds continue to gain interest in synthesis of chemical entities and exhibit various biological activities as anti-protozoal and anti-c
Antiprotozoal activities of traditional medicinal plants from the Garhwal region of North West Himalaya, India (Publications)
ETHNOPHARMACOLOGICAL RELEVANCE: In a search for new plant-derived biologically active compounds against protozoan parasites, an ethnopharmacological study was carried out to evaluate extracts from sel
Toll-like receptor 2 as a major gene for asthma in children of European farmers (Publications)
BACKGROUND: The finding that the prevalence of asthma and allergies is less frequent in children raised on animal farms has led to the conjecture that exposure to microbial products modifies immune re
Reproduktive Mortalität in der Schweiz zwischen 1952 und 1982 (Publications)
Reproductive mortality includes mortality attributable to pregnancy and childbirth and its sequelae, termination of pregnancy and contraception. The latter is mainly due to an increase of cardiovascul
The structure-activity relationship of the antimalarial ozonide arterolane (OZ277) (Publications)
The structure and stereochemistry of the cyclohexane substituents of analogues of arterolane (OZ277) had little effect on potency against Plasmodium falciparum in vitro. Weak base functional groups we