Modelling vertical transmission in vector-borne diseases with applications to Rift Valley fever (Publications)
We present two ordinary differential equation models for Rift Valley fever (RVF) transmission in cattle and mosquitoes. We extend existing models for vector-borne diseases to include an asymptomatic h
Human T cell epitopes of <em>Mycobacterium tuberculosis</em> are evolutionarily hyperconserved (Publications)
Mycobacterium tuberculosis is an obligate human pathogen capable of persisting in individual hosts for decades. We sequenced the genomes of 21 strains representative of the global diversity and six ma
Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents (Publications)
We report herein the synthesis and trypanocidal profile of new (E)-cinnamic N-acylhydrazones (NAHs) designed by exploiting molecular hybridization between the potent cruzain inhibitors (E)-1-(benzo[d]
The <em>in vitro</em> distribution of halofantrine in human blood and <em>Plasmodium falciparum</em>-parasitised red blood cells (Publications)
The in vitro distribution of the antimalarial drug halofantrine was measured in drug-preincubated whole blood after separation of the blood cells from the plasma according to their type. In normal blo
Underestimation of airflow obstruction among young adults using FEV1/FVC <70% as a fixed cut-off: a longitudinal evaluation of clinical and... (Publications)
BACKGROUND: Early detection of airflow obstruction is particularly important among young adults because they are more likely to benefit from intervention. Using the forced expiratory volume in 1 s (FE