Oral cholera vaccine use in Zanzibar: socioeconomic and behavioural features affecting demand and acceptance (Publications)
BACKGROUND: Cholera remains a serious public health problem in low-income countries despite efforts in the past to promote oral rehydration therapy as major treatment. In 2007, the majority of worldwi
Design and pre-clinical profiling of a <em>Plasmodium falciparum</em> MSP-3 derived component for a multi-valent virosomal malaria vaccine (Publications)
BACKGROUND: Clinical profiling of two components for a synthetic peptide-based virosomal malaria vaccine has yielded promising results, encouraging the search for additional components for inclusion i
Simulation of malaria epidemiology and control in the highlands of western Kenya (Publications)
BACKGROUND: Models of Plasmodium falciparum malaria epidemiology that provide realistic quantitative predictions of likely epidemiological outcomes of existing vector control strategies have the poten
Tribendimidine and albendazole for treating soil-transmitted helminths, <em>Strongyloides stercoralis</em> and <em>Taenia</em> spp.: open-label... (Publications)
BACKGROUND: Tribendimidine is an anthelminthic drug with a broad spectrum of activity. In 2004 the drug was approved by Chinese authorities for human use. The efficacy of tribendimidine against soil-t
Population hemoglobin mean and anemia prevalence in Papua New Guinea: new metrics for defining malaria endemicity? (Publications)
BACKGROUND: The hypothesis is that hemoglobin-based metrics are useful tools for estimating malaria endemicity and for monitoring malaria control strategies. The aim of this study is to compare popula
Comparative cost assessment of the Kato-Katz and FLOTAC techniques for soil-transmitted helminth diagnosis in epidemiological surveys (Publications)
ABSTRACT: BACKGROUND: The Kato-Katz technique is widely used for the diagnosis of soil-transmitted helminthiasis in epidemiological surveys and is believed to be an inexpensive method. The FLOTAC tech
Geostatistical model-based estimates of schistosomiasis prevalence among individuals aged </=20 years in West Africa (Publications)
BACKGROUND: Schistosomiasis is a water-based disease that is believed to affect over 200 million people with an estimated 97% of the infections concentrated in Africa. However, these statistics are la
Low efficacy of single-dose albendazole and mebendazole against hookworm and effect on concomitant helminth infection in Lao PDR (Publications)
BACKGROUND: Albendazole and mebendazole are increasingly deployed for preventive chemotherapy targeting soil-transmitted helminth (STH) infections. We assessed the efficacy of single oral doses of alb
Bayesian geostatistical modelling of malaria and lymphatic filariasis infections in Uganda: predictors of risk and geographical patterns of... (Publications)
BACKGROUND: In Uganda, malaria and lymphatic filariasis (causative agent Wuchereria bancrofti) are transmitted by the same vector species of Anopheles mosquitoes, and thus are likely to share common e