Bovine tuberculosis at a cattle-small ruminant-human interface in Meskan, Gurage region, central Ethiopia (Publications)
ABSTRACT: BACKGROUND: Bovine tuberculosis (BTB) is endemic in Ethiopian cattle. The aim of this study was to assess BTB prevalence at an intensive contact interface in Meskan Woreda (district) in catt
Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis (Publications)
Novel drugs to treat human African trypanosomiasis (HAT) are still urgently needed despite the recent addition of nifurtimox-eflornithine combination therapy (NECT) to WHO Model Lists of Essential Med
Structure-activity relationship studies on the macrolide exotoxin mycolactone of <em>Mycobacterium ulcerans</em> (Publications)
BACKGROUND: Mycolactones are a family of polyketide-derived macrolide exotoxins produced by Mycobacterium ulcerans, the causative agent of the chronic necrotizing skin disease Buruli ulcer. The toxin
Molecular characterization of <em>Mycobacterium bovis</em> strains isolated from cattle slaughtered at two abattoirs in Algeria (Publications)
BACKGROUND: Bovine Tuberculosis is prevalent in Algeria despite governmental attempts to control the disease. The objective of this study was to conduct, for the first time, molecular characterization
Rapid and accurate detection of <em>Mycobacterium tuberculosis</em> in sputum samples by Cepheid Xpert MTB/RIF assay - a clinical validation study (Publications)
BACKGROUND: A crucial impediment to global tuberculosis control is the lack of an accurate, rapid diagnostic test for detection of patients with active TB. A new, rapid diagnostic method, (Cepheid) Xp
Dynamics of <em>Schistosoma haematobium</em> egg output and associated infection parameters following treatment with praziquantel in school-aged... (Publications)
ABSTRACT: BACKGROUND: Praziquantel is the drug of choice in preventive chemotherapy targeting schistosomiasis. Increasing large-scale administration of praziquantel requires monitoring of drug efficac
Improving community coverage of oral cholera mass vaccination campaigns: lessons learned in Zanzibar (Publications)
BACKGROUND: Recent research in two cholera-endemic communities of Zanzibar has shown that a majority (?94%) of the adult population was willing to receive free oral cholera vaccines (OCVs). Since OCV
Global health initiative investments and health systems strengthening: a content analysis of global fund investments (Publications)
BACKGROUND: Millions of dollars are invested annually under the umbrella of national health systems strengthening. Global health initiatives provide funding for low- and middle-income countries throug