Ambient air pollution exposure estimation for the Global Burden of Disease 2013 (Publications)
Exposure to ambient air pollution is a major risk factor for global disease. Assessment of the impacts of air pollution on population health and evaluation of trends relative to other major risk facto
Assessing the impact of next-generation rapid diagnostic tests on <em>Plasmodium falciparum</em> malaria elimination strategies (Publications)
Mass-screen-and-treat and targeted mass-drug-administration strategies are being considered as a means to interrupt transmission of Plasmodium falciparum malaria. However, the effectiveness of such st
First report of <em>Echinococcus granulosus</em> (genotype G6) in a dog in Bamako, Mali (Publications)
Cystic echinococcosis is one of the most widespread and important helminthic zoonoses, caused by the larval stage of Echinococcus granulosus sensu lato. However, to date there is little information ab
Abietane-type diterpenoid amides with highly potent and selective activity against <em>Leishmania donovani</em> and <em>Trypanosoma cruzi</em> (Publications)
Dehydroabietylamine (1) was used as a starting material to synthesize a small library of dehydroabietyl amides by simple and facile methods, and their activities against two disease-causing trypanosom
Independent at heart: persistent association of altitude with ischaemic heart disease mortality after consideration of climate, topography and built... (Publications)
BACKGROUND: Living at higher altitude was dose-dependently associated with lower risk of ischaemic heart disease (IHD). Higher altitudes have different climatic, topographic and built environment prop
Early phase evaluation of SQ109 alone and in combination with rifampicin in pulmonary TB patients (Publications)
OBJECTIVES: SQ109, an asymmetrical diamine, is a novel anti-TB drug candidate. This first study in patients was done to determine safety, tolerability, pharmacokinetics and bacteriological effect of d
Population genomics of <em>Mycobacterium tuberculosis</em> in Ethiopia contradicts the virgin soil hypothesis for human tuberculosis in sub-Saharan... (Publications)
Colonial medical reports claimed that tuberculosis (TB) was largely unknown in Africa prior to European contact, providing a "virgin soil" for spread of TB in highly susceptible populations previously