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1. Southern East Asian origin and coexpansion of <em>Mycobacterium tuberculosis</em> Beijing family with Han Chinese (Publications)

   Southern East Asian origin and coexpansion of <em>Mycobacterium tuberculosis</em> Beijing family with Han Chinese

   Relevance:

   The Beijing family is the most successful genotype of Mycobacterium tuberculosis and responsible for more than a quarter of the global tuberculosis epidemic. As the predominant genotype in East Asia,

2. Maximizing microscopy as a diagnostic tool in peripheral health centres of BU endemic areas in Ghana (Publications)

   Maximizing microscopy as a diagnostic tool in peripheral health centres of BU endemic areas in Ghana

   Relevance:

   BACKGROUND: Buruli ulcer (BU) disease, a skin condition caused by Mycobacterium ulcerans (M. ulcerans) is endemic in remote rural areas. Disease diagnosis on clinical basis alone can be misleading, re

3. Dipeptidyl enoates as potent rhodesain inhibitors that display a dual mode of action [Communication] (Publications)

   Dipeptidyl enoates as potent rhodesain inhibitors that display a dual mode of action [Communication]

   Relevance:

   Dipeptidyl enoates were prepared through a high-yielding two-step synthetic route. They have a dipeptidic structure with a 4-oxoenoate moiety as a warhead with multiple reactive sites. Dipeptidyl enoa

4. Soudanones A-G: antifungal isochromanones from the ascomycetous fungus <em>Cadophora</em> sp. isolated from an iron mine (Publications)

   Soudanones A-G: antifungal isochromanones from the ascomycetous fungus <em>Cadophora</em> sp. isolated from an iron mine

   Relevance:

   One new isochromane (pseudoanguillosporin C, 2), seven isochromanones (soudanones A-G, 3-9), and six known analogues including 10 and 11 were isolated from a culture of the fungus Cadophora sp. 10-5-2

5. <em>In vivo</em> biosynthesis of terpene nucleosides provides unique chemical markers of <em>Mycobacterium tuberculosis</em> infection (Publications)

   <em>In vivo</em> biosynthesis of terpene nucleosides provides unique chemical markers of <em>Mycobacterium tuberculosis</em> infection

   Relevance:

   Although small molecules shed from pathogens are widely used to diagnose infection, such tests have not been widely implemented for tuberculosis. Here we show that the recently identified compound, 1-

6. Host-directed therapies for tackling multi-drug resistant TB - learning from the Pasteur-Bechamp debates (Publications)

   Host-directed therapies for tackling multi-drug resistant TB - learning from the Pasteur-Bechamp debates

   Relevance:

   Tuberculosis (TB) remains a global emergency causing an estimated 1.5 million deaths annually. For several decades the major focus of TB treatment has been on antibiotic development targeting Mycobact

7. Chemical constituents from <em>Waltheria indica</em> exert <em>in vitro</em> activity against <em>Trypanosoma brucei</em> and <em>T. cruzi</em> (Publications)

   Chemical constituents from <em>Waltheria indica</em> exert <em>in vitro</em> activity against <em>Trypanosoma brucei</em> and <em>T. cruzi</em>

   Relevance:

   Six extracts from the roots and the aerial parts of Waltheria indica L. (Malvaceae) were screened for their in vitro antitrypanosomal activity towards Trypanosoma brucei brucei STIB 427 strain, Trypan

8. TB or not TB - persistent cough, fever and night sweats in a 46-year-old traveler returning from South America (Publications)

   TB or not TB - persistent cough, fever and night sweats in a 46-year-old traveler returning from South America

   Relevance:

9. Towards host-directed therapies for tuberculosis [Comment] (Publications)

   Towards host-directed therapies for tuberculosis [Comment]

   Relevance:

   The treatment of tuberculosis is based on combinations of drugs that directly target Mycobacterium tuberculosis. A new global initiative is now focusing on a complementary approach of developing adjun

10. Using metal ratios to detect emissions from municipal waste incinerators in ambient air pollution data, atmospheric environment (Publications)

    Using metal ratios to detect emissions from municipal waste incinerators in ambient air pollution data, atmospheric environment

    Relevance: