Adopting clean fuels and technologies on school buses. Pollution and health impacts in children (Publications)
RATIONALE: More than 25 million American children breathe polluted air on diesel school buses. Emission reduction policies exist, but the health impacts to individual children have not been evaluated.
A novel multiple-stage antimalarial agent that inhibits protein synthesis (Publications)
There is an urgent need for new drugs to treat malaria, with broad therapeutic potential and novel modes of action, to widen the scope of treatment and to overcome emerging drug resistance. Here we de
Toward organometallic antischistosomal drug candidates (Publications)
In the recent years, there has been a growing interest in the use of novel approaches for the treatment of parasitic diseases such as schistosomiasis. Among the different approaches used, organometall
Assessment of source tracking methods for application in spring water (Publications)
For discriminating between human and animal faecal contamination in water, microbial source tracking (MST) approaches using different indicators have been employed. In the current study, a range of 10
Determinants of virological failure and antiretroviral drug resistance in Mozambique (Publications)
OBJECTIVES: The objective of this study was to inform public health actions to limit first-line ART failure and HIV drug resistance in Mozambique. METHODS: This was a cross-sectional study. HIV-1-infe
A global assessment of civil registration and vital statistics systems: monitoring data quality and progress (Publications)
Increasing demand for better quality data and more investment to strengthen civil registration and vital statistics (CRVS) systems will require increased emphasis on objective, comparable, cost-effect
Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness (Publications)
The global spread of dengue virus (DENV) infections has increased viral genetic diversity, some of which appear associated with greater epidemic potential. The mechanisms governing viral fitness in ep
Macyranones: structure, biosynthesis, and binding mode of an unprecedented epoxyketone that targets the 20S proteasome (Publications)
In our screening efforts to identify unique scaffolds from myxobacteria for the drug discovery process, we used LC-SPE-NMR-MS techniques to isolate six linear peptides, termed macyranone A-F, from Cys
Quantifying the health impacts of ambient air pollutants: recommendations of a WHO/Europe project (Publications)
OBJECTIVE: Quantitative estimates of air pollution health impacts have become an increasingly critical input to policy decisions. The WHO project "Health risks of air pollution in Europe-HRAPIE" was i