CCDC26, CDKN2BAS, RTEL1, and TERT polymorphisms in pediatric brain tumor susceptibility (Publications)
The role of genetic polymorphisms in pediatric brain tumor (PBT) etiology is poorly understood. We hypothesized that single nucleotide polymorphisms (SNPs) identified in genome-wide association studie
A heteromeric potassium channel involved in the modulation of the plasma membrane potential is essential for the survival of African trypanosomes (Publications)
Discovery of novel drug targets may lead to improved treatment of trypanosomiasis. We characterize here 2 gene products of Trypanosoma brucei that are essential for the growth of bloodstream form para
ARMADA: using motif activity dynamics to infer gene regulatory networks from gene expression data (Publications)
Analysis of gene expression data remains one of the most promising avenues toward reconstructing genome-wide gene regulatory networks. However, the large dimensionality of the problem prohibits the fi
Prices and mark-ups on antimalarials: evidence from nationally representative studies in six malaria-endemic countries (Publications)
The private for-profit sector is an important source of treatment for malaria. However, private patients face high prices for the recommended treatment for uncomplicated malaria, artemisinin combinati
Community awareness, use and preference for pandemic influenza vaccines in Pune, India (Publications)
Vaccination is a cornerstone of influenza prevention, but limited vaccine uptake was a problem worldwide during the 2009-2010 pandemic. Community acceptance of a vaccine is a critical determinant of i
Understanding suicide attempts among gay men from their self-perceived causes (Publications)
Gay men are at higher risk of suicidality. This paper describes the causes of suicide attempts as perceived by the men themselves and analyzes their impact on severity and recidivism. Mental health su
Reduction of anti-malarial consumption after rapid diagnostic tests implementation in Dar es Salaam: a before-after and cluster randomized controlled... (Publications)
BACKGROUND: Presumptive treatment of all febrile patients with anti-malarials leads to massive over-treatment. The aim was to assess the effect of implementing malaria rapid diagnostic tests (mRDTs) o
A novel approach for measuring the burden of uncomplicated <em>Plasmodium falciparum</em> malaria: application to data from Zambia (Publications)
Measurement of malaria burden is fraught with complexity, due to the natural history of the disease, delays in seeking treatment or failure of case management. Attempts to establish an appropriate cas
<em>Mycobacterium africanum</em>: review of an important cause of human tuberculosis in West Africa (Publications)
Mycobacterium africanum consists of two phylogenetically distinct lineages within the Mycobacterium tuberculosis complex, known as M. africanum West African 1 and M. africanum West African 2. These li