Searched for *.

1. The flipside of eradicating a disease; human African trypanosomiasis in a woman in rural Democratic Republic of Congo: a case report (Publications)

   The flipside of eradicating a disease; human African trypanosomiasis in a woman in rural Democratic Republic of Congo: a case report

   Relevance:

   Human African Trypanosomiasis (HAT) is a neglected disease caused by the protozoan parasites Trypanosoma brucei and transmitted by tsetse flies that progresses in two phases. Symptoms in the first pha

2. Validation of <em>Plasmodium falciparum</em> dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity (Publications)

   Validation of <em>Plasmodium falciparum</em> dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity

   Relevance:

   BACKGROUND: Malaria remains as a major global problem, being one of the infectious diseases that engender highest mortality across the world. Due to the appearance of resistance and the lack of an eff

3. Active dispersal of <em>Aedes albopictus</em>: a mark-release-recapture study using self-marking units (Publications)

   Active dispersal of <em>Aedes albopictus</em>: a mark-release-recapture study using self-marking units

   Relevance:

   BACKGROUND: Understanding the dispersal dynamics of invasive mosquito species is fundamental to improve vector surveillance and to target control efforts. Aedes albopictus has been deemed a poor flyer

4. Investigating the drivers of the spatio-temporal patterns of genetic differences between <em>Plasmodium falciparum</em> malaria infections in Kilifi... (Publications)

   Investigating the drivers of the spatio-temporal patterns of genetic differences between <em>Plasmodium falciparum</em> malaria infections in Kilifi County, Kenya

   Relevance:

   Knowledge of how malaria infections spread locally is important both for the design of targeted interventions aiming to interrupt malaria transmission and the design of trials to assess the interventi

5. Understanding the gap between access and use: a qualitative study on barriers and facilitators to insecticide-treated net use in Ghana (Publications)

   Understanding the gap between access and use: a qualitative study on barriers and facilitators to insecticide-treated net use in Ghana

   Relevance:

   BACKGROUND: Mass and continuous distribution channels have significantly increased access to insecticide-treated nets (ITNs) in Ghana since 2000. Despite these gains, a large gap remains between ITN a

6. Challenges in diagnosing scrub typhus among hospitalized patients with undifferentiated fever at a national tertiary hospital in northern Vietnam (Publications)

   Challenges in diagnosing scrub typhus among hospitalized patients with undifferentiated fever at a national tertiary hospital in northern Vietnam

   Relevance:

   BACKGROUND: Scrub typhus (ST) is a leading cause of non-malarial febrile illness in Southeast Asia, but evidence of its true disease burden is limited because of difficulties of making the clinical di

7. Targeting <em>Plasmodium </em>plasmepsin V: hitting two birds with one stone (Publications)

   Targeting <em>Plasmodium </em>plasmepsin V: hitting two birds with one stone

   Relevance:

   A recent report by Jennison et al. reveals an important role for plasmepsin V (PMV), an aspartyl protease, in the development of malaria transmission stages. The authors showed that PMV activity is cr

8. Stochastic protein alkylation by antimalarial peroxides (Publications)

   Stochastic protein alkylation by antimalarial peroxides

   Relevance:

   Antimalarial peroxides such as the phytochemical artemisinin or the synthetic ozonides arterolane and artefenomel undergo reductive cleavage of the pharmacophoric peroxide bond by ferrous heme, releas

9. Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay (Publications)

   Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay

   Relevance:

   BACKGROUND: Drug efficacy against kelch 13 mutant malaria parasites can be determined in vitro with the ring-stage survival assay (RSA). The conventional assay protocol reflects the exposure profile o

10. <em>Plasmodium</em> gametocytes display homing and vascular transmigration in the host bone marrow (Publications)

    <em>Plasmodium</em> gametocytes display homing and vascular transmigration in the host bone marrow

    Relevance:

    Transmission of Plasmodium parasites to the mosquito requires the formation and development of gametocytes. Studies in infected humans have shown that only the most mature forms of Plasmodium falcipar