Total synthesis and antitrypanosomal activity of janadolide and simplified analogues (Publications)
Janadolide is a cyclic depsipeptide natural product isolated from the marine cyanobacterium Okeania sp. Herein, we describe the total synthesis of janadolide, along with eight simplified analogues, vi
Health and economic burden of respiratory syncytial virus (RSV) disease and the cost-effectiveness of potential interventions against RSV among... (Publications)
BACKGROUND: Respiratory syncytial virus (RSV) frequently causes acute lower respiratory infection in children under 5, representing a high burden in Gavi-eligible countries (mostly low-income and lowe
Re-annotation of the <em>Theileria parva</em> genome refines 53% of the proteome and uncovers essential components of N-glycosylation, a conserved... (Publications)
BACKGROUND: The apicomplexan parasite Theileria parva causes a livestock disease called East coast fever (ECF), with millions of animals at risk in sub-Saharan East and Southern Africa, the geographic
A random forest approach to estimate daily particulate matter, nitrogen dioxide, and ozone at fine spatial resolution in Sweden (Publications)
Air pollution is one of the leading causes of mortality worldwide. An accurate assessment of its spatial and temporal distribution is mandatory to conduct epidemiological studies able to estimate long
Early life risk factors of motor, cognitive and language development: a pooled analysis of studies from low/middle-income countries (Publications)
OBJECTIVE: To determine the magnitude of relationships of early life Ffactors with child development in low/middle-income countries (LMICs). DESIGN: Meta-analyses of standardised mean differences (SMD
Cost of interventions to control schistosomiasis: a systematic review of the literature (Publications)
BACKGROUND: Schistosomiasis, a disease caused by blood flukes of the genus Schistosoma, belongs to the neglected tropical diseases. Left untreated, schistosomiasis can lead to severe health problems a
Mechanochemical formation of racemic praziquantel hemihydrate with improved biopharmaceutical properties (Publications)
Praziquantel (PZQ) is the first-line drug used against schistosomiasis, one of the most common parasitic diseases in the world. A series of crystalline structures including two new polymorphs of the p
Survive and thrive in Brazil: the Boa Vista Early Childhood program: study protocol of a stepped-wedge, randomized controlled trial (Publications)
BACKGROUND: A growing body of evidence suggests that early life health and developmental outcomes can be improved through parental support programs. The objective of this project was to test the feasi
Risk reduction of diarrhea and respiratory infections following a community health education program - a facility-based case-control study in rural... (Publications)
BACKGROUND: Diarrheal and acute respiratory infections remain a major cause of death in developing countries especially among children below 5 years of age. About 80% of all hospital attendances in Ke
