The microbiome antibiotic resistome: significant strategies toward microbiome-targeted therapeutic interventions in medicine (Publications)
Antibiotic resistance/drug resistance occurs in some, or less commonly all, subpopulations of microbes, usually bacteria, which can survive after exposure to one or more antibiotic environments. A mic
Europe-wide high-spatial resolution air pollution models are improved by including traffic flow estimates on all roads (Publications)
Road traffic is an important source of noise and air pollution. Modelling of air pollution and noise therefore requires detailed information on annual average daily traffic (AADT) flows on all roads.
Pilot use of a mycolactone-specific lateral flow assay for <em>Buruli ulcer</em>: a case report from Japan (Publications)
Buruli ulcer, caused by Mycobacterium (M.) ulcerans, is a neglected tropical disease (NTD) characterized by necrosis of the cutaneous tissue, predominantly affecting the limbs. The pathogenesis of thi
Optimising HIV spending in 12 eastern European and central Asian countries: a modelling study (Publications)
BACKGROUND: The eastern European and central Asian (EECA) region has the fastest growing HIV epidemic globally. We aimed to identify how HIV resources could be allocated for maximum health impact. MET
A novel barcoded nanopore sequencing workflow of high-quality, full-length bacterial 16S amplicons for taxonomic annotation of bacterial isolates and... (Publications)
Due to recent improvements, Nanopore sequencing has become a promising method for experiments relying on amplicon sequencing. We describe a flexible workflow to generate and annotate high-quality, ful
Burden of disease in Germany attributed to ambient particulate matter pollution : findings from the Global Burden of Disease Study 2019 (Publications)
INTRODUCTION: Ambient fine particulate matter pollution with a diameter less than 2.5 micrometers (PM(2.5)) is a significant risk factor for chronic noncommunicable diseases (NCDs), leading to a subst
Long-term results of hypofractionated radiotherapy with intra-prostatic boosts in men with intermediate- and high-risk prostate cancer: a phase II... (Publications)
AIMS: In the conventionally fractionated phase III FLAME prostate trial, focal boosts improved local control and biochemical disease-free survival (bDFS). We explored the toxicity and effectiveness of
The effects of climatic and non-climatic factors on malaria mortality at different spatial scales in western Kenya, 2008-2019 (Publications)
BACKGROUND: Malaria mortality is influenced by several factors including climatic and environmental factors, interventions, socioeconomic status (SES) and access to health systems. Here, we investigat
The effect of exposure to radiofrequency fields on cancer risk in the general and working population: a systematic review of human observational... (Publications)
BACKGROUND: The objective of this review was to assess the quality and strength of the evidence provided by human observational studies for a causal association between exposure to radiofrequency elec
Breaking the threshold: developing multivariable models using computer-aided chest X-ray analysis for tuberculosis triage (Publications)
BACKGROUND: Computer-aided detection (CAD) software packages quantify tuberculosis-compatible chest X-ray (CXR) abnormality as continuous scores. In practice, a threshold value is selected for binary