Transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland (Publications)
Most studies published to date consider single noise sources and the reported noise metrics are not informative about the peaking characteristics of the source under investigation. Our study focuses o
Asthma, COPD and overlap syndrome: a longitudinal study in young European adults (Publications)
We compared risk factors and clinical characteristics, 9-year lung function change and hospitalisation risk across subjects with the asthma-chronic obstructive pulmonary disease (COPD) overlap syndrom
Heterogeneity of obesity-asthma association disentangled by latent class analysis, the SAPALDIA cohort (Publications)
Although evidence for the heterogeneity of asthma accumulated, consensus for definitions of asthma phenotypes is still lacking. Obesity may have heterogeneous effects on various asthma phenotypes. We
Adult onset asthma and interaction between genes and active tobacco smoking: the GABRIEL consortium (Publications)
BACKGROUND: Genome-wide association studies have identified novel genetic associations for asthma, but without taking into account the role of active tobacco smoking. This study aimed to identify nove
Genes interacting with occupational exposures to low molecular weight agents and irritants on adult-onset asthma in three European studies (Publications)
BACKGROUND: The biological mechanisms by which cleaning products and disinfectants - an emerging risk factor - affect respiratory health remain incompletely evaluated. Studying genes by environment in
Associations of novel and traditional vascular biomarkers of arterial stiffness: results of the SAPALDIA 3 cohort study (Publications)
BACKGROUND AND OBJECTIVES: There is a lack of evidence concerning associations between novel parameters of arterial stiffness as cardiovascular risk markers and traditional structural and functional v
Prevalence of renal impairment and its association with cardiovascular risk factors in a general population: results of the Swiss SAPALDIA study (Publications)
BACKGROUND: Impaired renal function is evolving as an independent marker of the risk of cardiovascular morbidity and mortality. Little is known about the prevalence of impaired renal function and its
A large-scale, consortium-based genomewide association study of asthma (Publications)
BACKGROUND: Susceptibility to asthma is influenced by genes and environment; implicated genes may indicate pathways for therapeutic intervention. Genetic risk factors may be useful in identifying subt
Prevalence of atopy and respiratory allergic diseases in the elderly SAPALDIA population (Publications)
Background: Because of changing world demographics, the elderly population is steadily increasing. Few studies have assessed the prevalence of atopy and allergic diseases in elderly persons with objec