Specificity, cross-reactivity and function of antibodies elicited by Zika virus infection (Publications)
Zika virus (ZIKV), a mosquito-borne flavivirus with homology to Dengue virus (DENV), has become a public health emergency. By characterizing memory cells from ZIKV-infected patients, we dissected ZIKV
Efficacy and reinfection with soil-transmitted helminths 18-weeks post-treatment with albendazole-ivermectin, albendazole-mebendazole,... (Publications)
BACKGROUND: Preventive chemotherapy with albendazole or mebendazole is the current strategy to control soil-transmitted helminth (STH) infections (i.e. Ascaris lumbricoides, hookworm and Trichuris tri
Associations of inter- and intraday temperature change with mortality (Publications)
In this study we evaluated the association between temperature variation and mortality and compared it with the contribution due to mean daily temperature in 6 cities with different climates. Quasi-Po
Sociocultural determinants of anticipated oral cholera vaccine acceptance in three African settings: a meta-analytic approach (Publications)
BACKGROUND: Controlling cholera remains a significant challenge in Sub-Saharan Africa. In areas where access to safe water and sanitation are limited, oral cholera vaccine (OCV) can save lives. Establ
Managing research and surveillance projects in real-time with a novel open-source eManagement tool designed for under-resourced countries (Publications)
OBJECTIVE: A software tool is developed to facilitate data entry and to monitor research projects in under-resourced countries in real-time. METHODS: The eManagement tool "odk_planner" is written in t
Stakeholders' opinions and questions regarding the anticipated malaria vaccine in Tanzania (Publications)
BACKGROUND: Within the context of combined interventions, malaria vaccine may provide additional value in malaria prevention. Stakeholders' perspectives are thus critical for informed recommendation o
Development and validation of an enantioselective LM-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in... (Publications)
Praziquantel (PZQ) is the treatment of choice against various trematode and cestode infections. To study the pharmacokinetics of PZQ in patients infected with the liver fluke Opisthorchis viverrini, w
Structure-activity relationship studies of orally active antimalarial 2,4-diamino-thienopyrimidines (Publications)
Based on the initial optimization of orally active antimalarial 2,4-diamino-thienopyrimidines and with the help of metabolite identification studies, a second generation of derivatives involving chang
Near-roadway air pollution and coronary heart disease: burden of disease and potential impact of a greenhouse gas reduction strategy in southern... (Publications)
BACKGROUND: Several studies have estimated the burden of coronary heart disease (CHD) mortality from ambient regional particulate matter
A bundle of services increased ascertainment of tuberculosis among HIV-infected individuals enrolled in a HIV cohort in rural sub-Saharan Africa (Publications)
OBJECTIVES: To report on trends of tuberculosis ascertainment among HIV patients in a rural HIV cohort in Tanzania, and assessing the impact of a bundle of services implemented in December 2012, consi