Analysis of subtelomeric virulence gene families in <em>Plasmodium falciparum</em> by comparative transcriptional profiling (Publications)
The Plasmodium falciparum genome is equipped with several subtelomeric gene families that are implicated in parasite virulence and immune evasion. Members of these families are uniformly positioned wi
Tegumental alterations in juvenile <em>Schistosoma haematobium</em> harboured in hamsters following artemether treatment (Publications)
We report the findings of a detailed temporal study on tegumental alterations in juvenile Schistosoma haematobium, induced by artemether, using scanning electron microscopy. Hamsters infected with S.
Effect of praziquantel together with artemether on <em>Schistosoma japonicum </em>parasites of different ages in rabbits (Publications)
The efficacy of combined treatment with praziquantel and artemether against infection with Schistosoma japonicum was tested on infected rabbits, in which 7-to 14-day-old schistosomules and 42-day-old
Effect of artemether administered alone or in combination with praziquantel to mice infected with <em>Plasmodium berghei </em>or <em>Schistosoma... (Publications)
The artemisinins have become key drugs for the treatment and control of malaria, particularly within artemisinin-based combination therapies. Since the artemisinins also exhibit antischistosomal prope
Improved detection of <em>Rhodococcus coprophilus</em> with a new quantitative PCR assay (Publications)
Agricultural practices, such as spreading liquid manure or the utilisation of land as animal pastures, can result in faecal contamination of water resources. Rhodococcus coprophilus is used in microbi
Effect of particulate air pollution on lung function in adult and pediatric subjects in a Seattle panel study (Publications)
STUDY OBJECTIVE: To determine whether increased exposure to particulate matter air pollution (PM), measured with personal, residential, or central site monitoring, was associated with pulmonary functi
Immunogenicity and safety of yellow fever vaccination for 102 HIV-infected patients (Publications)
BACKGROUND: Yellow fever vaccine (17DV) has been investigated incompletely in human immunodeficiency virus (HIV)-infected patients, and adequate immunogenicity and safety are of concern in this popula
Efficacy and cost-effectiveness of environmental management for malaria control (Publications)
Roll back malaria (RBM) aims at halving the current burden of the disease by the year 2010. The focus is on sub-Saharan Africa, and it is proposed to implement efficacious and cost-effective control s
Oral artemether for prevention of <em>Schistosoma mansoni</em> infection: randomised controlled trial (Publications)
BACKGROUND: Chemotherapy with praziquantel is the current strategy of choice to control schistosomiasis. However, in view of concern about praziquantel tolerance or resistance, new drugs are needed. A
