Synthesis and structure-activity analysis of new phosphonium salts with potent activity against African trypanosomes (Publications)
A series of 73 bisphosphonium salts and 10 monophosphonium salt derivatives were synthesized and tested in vitro against several wild type and resistant lines of Trypanosoma brucei (T. b. rhodesiense
Genome-based health literacy: a new challenge for public health genomics (Publications)
So far health literacy has not been sufficiently discussed in the context of public health genomics. Primarily, not genomic but rather genome-based health information needs to be addressed taking into
Informed choices for attaining the Millennium Development Goals: towards an international cooperative agenda for health-systems research (Publications)
Health systems constraints are impeding the implementation of major global initiatives for health and the attainment of the Millennium Development Goals (MDGs). Research could contribute to overcoming
Studies on <em>Dipetalonema viteae</em> (Filarioidea). 4. Passive transfer of immunity to circulating microfilariae by spleen cells (Publications)
Passive transfer experiments provided clear evidence for a role of spleen cells in the immunity of hamsters against Dipetalonema viteae microfilariae. 106 or more spleen cells from postpatent (amicrof
New treatment option for second stage African sleeping sickness: In vitro and in vivo efficacy of aza analogs of DB289 (Publications)
African sleeping sickness is a fatal parasitic disease and all drugs currently in use for treatment have strong liabilities. It is essential to find new, effective and less toxic drugs ideally with or
Different strategies to overcome the effect of carbimazole on high- and low-dose radioiodine therapy: results from continuous dose-effect models (Publications)
BACKGROUND: Until now, it remains elusive which strategy - antithyroid drug withdrawal or increased radioiodine target doses - should be preferred to avoid the detrimental effect of antithyroid drugs