Effectiveness of three sampling approaches for optimizing mapping and preventive chemotherapy against <em>Schistosoma mansoni</em> in the western part... (Publications)
The elimination of schistosomiasis as a public health problem by 2030 is one of the main goals put forth in the World Health Organization's roadmap for neglected tropical diseases. This study aimed to
Identification of potent and reversible piperidine carboxamides that are species-selective orally active proteasome inhibitors to treat malaria (Publications)
Malaria remains a global health concern as drug resistance threatens treatment programs. We identified a piperidine carboxamide (SW042) with anti-malarial activity by phenotypic screening. Selection o
Intervention effect of targeted workplace closures may be approximated by single-layered networks in an individual-based model of COVID-19 control (Publications)
Individual-based models of infectious disease dynamics commonly use network structures to represent human interactions. Network structures can vary in complexity, from single-layered with homogeneous
Barriers and facilitators to health insurance enrolment among people working in the informal sector in Morogoro, Tanzania (Publications)
Background: Health insurance is a crucial pathway towards the achievement of universal health coverage. In Tanzania, health-financing reforms are underway to speed up universal health coverage in the
Indigenous emergence and spread of <em>kelch13</em> C469Y artemisinin-resistant <em>Plasmodium falciparum</em> in Uganda (Publications)
Artemisinin-based combination therapies (ACTs) were introduced as the standard of care for uncomplicated malaria in Africa almost two decades ago. Recent studies in East Africa have reported a gradual
Resistance-informed versus empirical management of viraemia in children and adolescents with HIV in Lesotho and Tanzania (GIVE MOVE trial): a... (Publications)
BACKGROUND: Children and adolescents with HIV taking antiretroviral therapy (ART) have high rates of viraemia. We assessed if genotypic resistance testing (GRT) to inform onward treatment improved tre