Medical use of cannabis in Switzerland: analysis of approved exceptional licences (Publications)
AIMS OF THE STUDY: In recent years, the Swiss Federal Office of Public Health (FOPH) granted exceptional licenses for the medical use of cannabinoids, typically for 6 months with possible extensions.
Transcriptional profiling defines dynamics of parasite tissue sequestration during malaria infection (Publications)
BACKGROUND: During intra-erythrocytic development, late asexually replicating Plasmodium falciparum parasites sequester from peripheral circulation. This facilitates chronic infection and is linked to
Effects of liver-stage clearance by Primaquine on gametocyte carriage of <em>Plasmodium vivax</em> and <em>P. falciparum</em> (Publications)
BACKGROUND: Primaquine (PQ) is the only currently licensed antimalarial that prevents Plasmodium vivax (Pv) relapses. It also clears mature P. falciparum (Pf) gametocytes, thereby reducing post-treatm
Antileukemic ancistrobenomine B and related 5,1′-coupled naphthylisoquinoline alkaloids from the Chinese liana <em>Ancistrocladus tectorius</em> (Publications)
A striking feature of the metabolite pattern of the Southeast Asian liana Ancistrocladus tectorius (Ancistrocladaceae) is the predominance of 5,1'-coupled naphthylisoquinoline alkaloids. About 20 alka
Target product profile for a diagnostic assay to differentiate between bacterial and non-bacterial infections and reduce antimicrobial overuse in... (Publications)
Acute fever is one of the most common presenting symptoms globally. In order to reduce the empiric use of antimicrobial drugs and improve outcomes, it is essential to improve diagnostic capabilities.
Synthesis and potent antiprotozoal activity of mono/di amidino 2-anilinobenz-imidazoles versus <em>Plasmodium falciparum</em> and <em>Trypanosoma... (Publications)
A series of mono and dicationic new 2-anilinobenzimidazole carboxamidines were prepared in a four step process starting from 4-amino-3-nitrobenzonitrile and corresponding o-phenylenediamines. Their an