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1. Metabolic, pharmacokinetic, and activity profile of the liver stage antimalarial (RC-12) (Publications)

   Metabolic, pharmacokinetic, and activity profile of the liver stage antimalarial (RC-12)

   Relevance:

   The catechol derivative RC-12 (WR 27653) (1) is one of the few non-8-aminoquinolines with good activity against hypnozoites in the gold-standard Plasmodium cynomolgi-rhesus monkey (Macaca mulatta) mod

2. Use of index testing to close the gap in HIV diagnosis among older people in Rwanda: analysis of data from a public health programme (Publications)

   Use of index testing to close the gap in HIV diagnosis among older people in Rwanda: analysis of data from a public health programme

   Relevance:

   BACKGROUND: As Rwanda inches closer to the UNAIDS HIV first 95 of knowing one's HIV status by 2030, finding the remaining HIV-positive individuals could be difficult by use of passive methods. Index t

3. Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 (Publications)

   Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

   Relevance:

   Drug resistance and a dire lack of transmission-blocking antimalarials hamper malaria elimination. Here, we present the pantothenamide MMV693183 as a first-in-class acetyl-CoA synthetase (AcAS) inhibi

4. Gut microbiota targeted approach in the management of chronic liver diseases (Publications)

   Gut microbiota targeted approach in the management of chronic liver diseases

   Relevance:

   The liver is directly connected to the intestines through the portal vein, which enables the gut microbiota and gut-derived products to influence liver health. There is accumulating evidence of decrea

5. Together yet apart: remedies for tensions between volunteers and health care professionals in inter-professional collaboration (Publications)

   Together yet apart: remedies for tensions between volunteers and health care professionals in inter-professional collaboration

   Relevance:

   While volunteering is an essential factor in service delivery in many societal areas, the inclusion of volunteers in formal settings can also lead to tensions. In this article, we combine the literatu

6. Inequality in the quality of health services: wealth, content of care, and the price of antenatal consultations in the Democratic Republic of Congo (Publications)

   Inequality in the quality of health services: wealth, content of care, and the price of antenatal consultations in the Democratic Republic of Congo

   Relevance:

   We use unique data on direct observations of patient-provider interactions linked to detailed patient exit interviews and household surveys to study the relationship between patients’ socioeconomic st

7. Strong off-target antibody reactivity to malarial antigens induced by RTS,S/AS01E vaccination is associated with protection (Publications)

   Strong off-target antibody reactivity to malarial antigens induced by RTS,S/AS01E vaccination is associated with protection

   Relevance:

   The RTS,S/AS01E vaccine targets the circumsporozoite protein (CSP) of the Plasmodium falciparum parasite. Using protein microarrays, levels of IgG to 1,000 P. falciparum antigens were measured in 2,13

8. Does global health governance walk the talk? Gender representation in World Health Assemblies, 1948-2021 (Publications)

   Does global health governance walk the talk? Gender representation in World Health Assemblies, 1948-2021

   Relevance:

   BACKGROUND: While an estimated 70%-75% of the health workforce are women, this is not reflected in the leadership roles of most health organisations-including global decision-making bodies such as the

9. Discovery of novel quinoline-based proteasome inhibitors for human African trypanosomiasis (HAT) (Publications)

   Discovery of novel quinoline-based proteasome inhibitors for human African trypanosomiasis (HAT)

   Relevance:

   Human African Trypanosomiasis (HAT) is a vector-borne disease caused by kinetoplastid parasites of the Trypanosoma genus. The disease proceeds in two stages, with a hemolymphatic blood stage and a men

10. Deconstructing design thinking as a tool for the implementation of a population health initiative (Publications)

    Deconstructing design thinking as a tool for the implementation of a population health initiative

    Relevance:

    BACKGROUND: The translation of evidence-based practices and rapid uptake of innovations into global health practice is challenging. Design thinking is a consultative process involving multiple stakeho