Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and... (Publications)
decreased from 59.7 % (95 % CI: 54.5-64.9) on day 1 to 6.7 % (95 % CI: 4.8-8.7) on day 2 and 0.9 % (95 % CI: 0.5-1.2) on day 3. The 95th percentile of observed day 3 PPR was 5.3 %. Independent risk factors [...] P 37.5 degrees C) (AOR = 1.50 (95 % CI: 1.06-2.13), P = 0.022); severe anaemia (AOR = 2.04 (95 % CI: 1.21-3.44), P = 0.008); areas of low/moderate transmission setting (AOR = 2.71 (95 % CI: 1.38-5.36), [...] rapid early parasitological clearance across the sites assessed in Sub-Saharan...
Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015 (Publications)
improved by a median of 7.9 (IQR 5.0-10.4), and gains on the MDG index (a median change of 10.0 [6.7-13.1]) exceeded that of the non-MDG index (a median change of 5.5 [2.1-8.9]). Since 2000, pronounced [...] index was 59.3 (95% uncertainty interval 56.8-61.8) and varied widely by country, ranging from 85.5 (84.2-86.5) in Iceland to 20.4 (15.4-24.9) in Central African Republic. SDI was a good predictor of the [...] pronounced progress occurred for indicators such as met need with modern...
Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and... (Publications)
decreased from 59.7 % (95 % CI: 54.5-64.9) on day 1 to 6.7 % (95 % CI: 4.8-8.7) on day 2 and 0.9 % (95 % CI: 0.5-1.2) on day 3. The 95th percentile of observed day 3 PPR was 5.3 %. Independent risk factors [...] P 37.5 degrees C) (AOR = 1.50 (95 % CI: 1.06-2.13), P = 0.022); severe anaemia (AOR = 2.04 (95 % CI: 1.21-3.44), P = 0.008); areas of low/moderate transmission setting (AOR = 2.71 (95 % CI: 1.38-5.36), [...] rapid early parasitological clearance across the sites assessed in Sub-Saharan...
Global, regional, and national burden of meningitis and its aetiologies, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019 (Publications)
largest reduction in the number of deaths among children younger than 5 years (76·5% [69·5-81·8]), followed by N meningitidis (72·3% [64·4-78·5]) and viruses (58·2% [47·1-67·3]). INTERPRETATION: Substantial progress [...] in children younger than 5 years, with 112 000 deaths (87 400-145 000) and 1·28 million incident cases (0·947-1·71) in 2019. Age-standardised mortality rates decreased from 7·5 (6·6-8·4) per 100 000 population
Urine-Xpert Ultra for the diagnosis of tuberculosis in people living with HIV: a prospective, multicentre, diagnostic accuracy study (Publications)
complete. FINDINGS: Between Dec 13, 2019, and Aug 5, 2021, 3528 potentially eligible individuals were screened and 1731 were enrolled, of whom 1602 (92·5%) were classifiable by the eMRS (median age 40 years [...] years [IQR 33-48], 838 [52·3%] of 1602 were female, 764 [47·7%] were male, 937 [58·5%] were outpatients, 665 [41·5%] were inpatients, median CD4 count was 374 cells per μL [IQR 138-630], and 254 [15·9%] [...] Urine-Xpert Ultra and AlereLAM were 21·1% (95% CI 17·6-25·1), and 30·5%...
Tuberkulintests und Tuberkuloseinzidenz bei Schülern - Erfahrungen aus dem Schularztamt Basel-Stadt (Publications)
this rate was between a minimum of 6.3% and maximum 14.5%. Since the children had not been tested for four years previously, an incidence between 1.5 an 3% can be calculated for this age group
Tuberkulintests und Tuberkuloseinzidenz bei Schülern - Erfahrungen aus dem Schularztamt Basel-Stadt (Publications)
this rate was between a minimum of 6.3% and maximum 14.5%. Since the children had not been tested for four years previously, an incidence between 1.5 an 3% can be calculated for this age group
Disentangling associations between multiple environmental exposures and all-cause mortality: an analysis of European administrative and traditional... (Publications)
for NO2. The CRI of air pollutants (PM2.5 or NO2) plus NDVI and mean warm season temperature resulted in a stronger effect compared to single-exposure HRs: [PM2.5 pooled HR: 1.061 (95% CI 1.021–1.102); [...] hybrid land use regression models and satellite data for: air pollution [fine particulate matter (PM2.5), nitrogen dioxide (NO₂), black carbon (BC), warm season ozone (O3)], land/built environment [normalized [...] out of approximately 204 million person-years. In administrative cohorts,...
Seroprevalence and risk factors for Q fever and Rift Valley fever in pastoralists and their livestock in Afar, Ethiopia: a One Health approach (Publications)
highest seroprevalence (8.3%, 95%CI 3.3-19.2), followed by goats (2.7%; 95%CI 1.4-5.1), sheep (2.5%; 95%CI 1.0-5.9) and camels (1.8%; 95%CI 0.4-6.9). Human Q fever seropositivity was found to be associated [...] (95%CI 10.4-24.6) and 8.8% in cattle (95%CI 5.0-15.0). For Rift Valley fever the seroprevalence in pastoralists was 6.1% (95%CI 3.3-11.0) and 3.9% (95%CI 2.6-5.7) in livestock overall; cattle had the highest
Disentangling associations between multiple environmental exposures and all-cause mortality: an analysis of European administrative and traditional... (Publications)
NO(2). The CRI of air pollutants (PM(2.5) or NO(2)) plus NDVI and mean warm season temperature resulted in a stronger effect compared to single-exposure HRs: [PM(2.5) pooled HR: 1.061 (95% CI 1.021-1.102); [...] hybrid land use regression models and satellite data for: air pollution [fine particulate matter (PM(2.5)), nitrogen dioxide (NO₂), black carbon (BC), warm season ozone (O(3))], land/built environment [normalized [...] out of approximately 204 million person-years. In administrative...