Effectiveness of rectal artesunate as pre-referral treatment for severe malaria in children under 5 years of age: a multi-country observational study (Publications)
BACKGROUND: To prevent child deaths from severe malaria, early parenteral treatment is essential. Yet, in remote rural areas, accessing facilities offering parenteral antimalarials may be difficult. A
Mortality and morbidity effects of long-term exposure to low-level PM2.5, BC, NO2, and O3: an analysis of European cohorts in the ELAPSE project (Publications)
= 1.11, 1.16) for an increase of 5 mug/m(3) PM2.5, 1.09 (CI = 1.07, 1.10) for an increase of 10 mug/m(3) NO2, and 1.08 (CI = 1.06, 1.10) for an increase of 0.5 x 10(-5)/m BC for natural-cause mortality [...] = 1.02, 1.09) for an increase of 5 mug/m(3) PM2.5, 1.04 (CI = 1.02, 1.07) for an increase of 10 mug/m(3) NO2, and 1.04 (CI = 1.02, 1.06) for an increase of 0.5 x 10(-5)/m BC, and 0.95 (CI = 0.93, 0.98) [...] investigate whether the associations persisted below specific concentration values....
Age and cancer incidence in 5.2 million people with HIV: the South African HIV Cancer Match study (Publications)
Using natural splines, we modelled cancer incidence rates as a function of age. RESULTS: We included 5,222,827 PWH with 29,580 incident cancer diagnoses - most commonly cervical cancer (n = 7418), Kaposi
A satellite-based spatio-temporal machine learning model to reconstruct daily PM2.5 concentrations across Great Britain (Publications)
matter (PM2.5) levels across Great Britain between 2008–2018. This high-resolution model consists of random forest (RF) algorithms applied in four stages. Stage-1 augments monitor-PM2.5 series using [...] spatial and spatio-temporal variables to build a prediction model for PM2.5. Stage-4 applies Stage-3 models to estimate daily PM2.5 concentrations over a 1 km grid. The RF architecture performed well in all [...] epidemiological analyses to assess health risks associated with both short- and...
Estimating urban <em>PM</em>10 and <em>PM</em>2.5 concentrations, based on synergistic MERIS/AATSR aerosol observations, land cover and morphology... (Publications)
approaches for quantitative estimation of daily mean Particulate Matter (PM) concentrations. Both fine (PM2.5) and coarse (PM10) concentrations were estimated over the area of London (UK) for the 2002–2012 time
Macrophage susceptibility to infection by Ghanaian <em>Mycobacterium tuberculosis</em> complex lineages 4 and 5 varies with self-reported ethnicity (Publications)
BACKGROUND: The epidemiology of Mycobacterium tuberculosis complex (MTBC) lineage 5 (L5) infections in Ghana revealed a significantly increased prevalence in Ewes compared to other self-reported ethnic [...] 001), translating into a higher bacillary load on day 7 (p < 0.001) compared to L5, despite the higher replication rate of L5 in Ewe MDMs (fold change: 1.4 vs. 1.2, p = 0.03) among the controls. On the contrary [...] phagocytic uptake of L5 (p < 0.001) compared to L4, also translating into a...
NO2 and PM2.5 exposures and lung function in Swiss adults: estimated effects of short-term exposures and long-term exposures with and without... (Publications)
-18.5 ml [-26.5, -10.5]). A 10mug/m3 increase in 1-y mean NO2 was also associated with lower FEV1 (-7.7 ml; -15.9, 0.5) and FVC (-21.6 ml; -31.9, -11.4), as was a 10mug/m3 increase in 1-y mean PM2.5 (FEV1: [...] dioxide (NO2) and particulate matter with an aerodynamic diameter of less than or equal to 2.5. microns (PM2.5) exposures on lung function has been investigated mainly in children and less in adults. Furthermore [...] NO2 and PM2.5 on the day of the pulmonary function test was associated...
Effectiveness of school-based preventive chemotherapy strategies for sustaining the control of schistosomiasis in Côte d’Ivoire: results of a 5-year... (Publications)
thick smears, among children aged 9-12 years at the time of each survey. First-grade children, aged 5-8 years who had never received praziquantel, were also tested at baseline and at the end of the study [...] final year, we observed the lowest prevalence of 10.4% in arm 1, compared to 18.2% in arm 2 and 17.5% in arm 3. The comparison between arms 1 and 2 estimated an odds ratio (OR) of 0.52 but the difference [...] final year survey were observed in arm 1 (7.9 eggs per gram of stool (EPG))....
Evaluation of the ERA5 reanalysis-based universal thermal climate index on mortality data in Europe (Publications)
ERA5 – the latest global climate reanalysis from the European Centre for Medium-Range Weather Forecasts (ECMWF) – as a health-related tool. Employing a novel ERA5-based thermal comfort dataset ERA5-HEAT [...] performance of ERA5-based UTCI, we compared its effects on mortality with those for the station-based UTCI data. In order to assess the additional effect of the UTCI, the performance of ERA5-and station-based [...] UTCI distribution. The comparison of exposure-response relationships between...
Elektromagnetische Felder des Mobilfunks im Zuge des aktuellen 5G-Netzausbaus Technische Aspekte und biologische Wirkungen im unteren Frequenzbereich... (Publications)
wurde in Deutschland im Jahr 2019 mit der Einführung des Mobilfunks der fünften Generation (5G) begonnen. Der 5G-Mobilkommunikationsstandard wird als Kerntechnologie für die Digitalisierung der Industrie [...] 7 Gigahertz (Frequency Range 1, FR1), der auch in den aktuellen 5G-Netzen genutzt wird. Zusätzlich werden besondere technische Aspekte der neuen 5G-Technologie betrachtet und ihre Auswirkungen auf die zu erwartende [...] erwartende Hochfrequenzimmission und die Exposition der Bevölkerung...