Inhibitors of PEX14 disrupt protein import into glycosomes and kill <em>Trypanosoma</em> parasites (Publications)
glycosomal/peroxisomal import that depends on the PEX14-PEX5 protein-protein interaction. We developed small molecules that efficiently disrupt the PEX14-PEX5 interaction. This results in mislocalization of glycosomal
Prévalence des diarrhées infantojuvéniles dans deux districts de Nouakchott (Mauritanie) en 2008: analyse de l'influence de l'hygiène du milieu... (Publications)
an average prevalence of 14.8% that varied by age (23.6% in children younger than 5 years and 9.7% among children aged 5 to 14 years) and area (16.8% in Tevragh-Zeina and 28.3% in Sebkha). The univariate
Antiprotozoal activities of heterocyclic-substituted xanthones from the marine-derived fungus <em>Chaetomium</em> sp (Publications)
an IC50 value of 0.5 microg/mL without being cytotoxic toward cultured eukaryotic cells. Compound 3 displayed a moderate activity against Trypanosoma cruzi with an IC50 value of 1.5 microg/mL
Diarrhoea among children aged under five years and risk factors in informal settlements: a cross-sectional study in Cape Town, South Africa (Publications)
diarrhoea among children aged under five years (U5D) and water use, sanitation, hygiene, and socio-economics factors in low-income communities. The study investigated U5D and the associated risk factors in the
The Basel early-detection-of-psychosis (FEPSY)-study--design and preliminary results (Publications)
examined extensively and followed-up for at least 5 years to detect actual transition to psychosis. RESULTS: Of 50 subjects who have been followed up for 1-5 years by now, 16 have progressed to frank psychosis
Increased incidence of Guillain-Barré syndrome after surgery (Publications)
with GBS in the study population and those reported previously in literature. RESULTS: Six of 63 (9.5%) GBS cases had had a surgery within 6 weeks prior to GBS. The relative risk of developing GBS during [...] surgery is 13.1 times higher than the normal incidence in the study population (95% confidence interval: 5.68, 30.3; P
Successful treatment of acute mountain sickness with dexamethasone (Publications)
sickness score decreased significantly from 5.4 to 1.3, and eight of 17 patients became totally asymptomatic. Mean arterial oxygen saturation rose from 75.5% to 82.0%, and there was a small increase in
The Basel early-detection-of-psychosis (FEPSY)-study--design and preliminary results (Publications)
examined extensively and followed-up for at least 5 years to detect actual transition to psychosis. RESULTS: Of 50 subjects who have been followed up for 1-5 years by now, 16 have progressed to frank psychosis
Increased incidence of Guillain-Barré syndrome after surgery (Publications)
with GBS in the study population and those reported previously in literature. RESULTS: Six of 63 (9.5%) GBS cases had had a surgery within 6 weeks prior to GBS. The relative risk of developing GBS during [...] surgery is 13.1 times higher than the normal incidence in the study population (95% confidence interval: 5.68, 30.3; P
Successful treatment of acute mountain sickness with dexamethasone (Publications)
sickness score decreased significantly from 5.4 to 1.3, and eight of 17 patients became totally asymptomatic. Mean arterial oxygen saturation rose from 75.5% to 82.0%, and there was a small increase in