Estimating the global burden of endemic canine rabies (Publications)
prophylaxis (PEP, 20%) and lost income whilst seeking PEP (15.5%), with only limited costs to the veterinary sector due to dog vaccination (1.5%), and additional costs to communities from livestock losses [...] CIs: 1.6-10.4 million) disability-adjusted life years (DALYs) and 8.6 billion USD (95% CIs: 2.9-21.5 billion) economic losses annually. The largest component of the economic burden is due to premature
The effect of air pollution on lung development from 10 to 18 years of age (Publications)
(P=0.005), acid vapor (P=0.004), particulate matter with an aerodynamic diameter of less than 2.5 microm (PM(2.5)) (P=0.04), and elemental carbon (P=0.007), even after adjustment for several potential confounders [...] expected FEV(1) of less than 80 percent) was 4.9 times as great at the highest level of exposure to PM(2.5) as at the lowest level of exposure (7.9 percent vs. 1.6 percent, P=0.002). CONCLUSIONS: The results
Microbial and chemical contamination of water, sediment and soil in the Nakivubo wetland area in Kampala, Uganda (Publications)
showed mean concentrations of TTCs of 2.9 x 10(5) colony-forming units (CFU)/100 mL. Mean E. coli was 9.9 x 10(4) CFU/100 mL. Hookworm eggs were found in 13.5 % of the water samples. Mean concentrations of [...] of iron (Fe), copper (Cu) and cadmium (Cd) were 21.5, 3.3 and 0.14 mg/L, respectively. In soil samples, we found a mean lead (Pb) concentration of 132.7 mg/L. In yams, concentrations of Cd, chromium (Cr)
Childhood air pollutant exposure and carotid artery intima-media thickness in young adults (Publications)
(SD) increase in childhood (aged 0-5 years) or elementary school (aged 6-12) O(3) exposure was associated with a 7.8 mum (95% CI -0.3, 15.9) or 10.1 mum (95% CI 1.8, 18.5) higher CIMT, respectively. Lifetime [...] exposure to O(3) showed similar but non-significant associations. No associations were observed for PM(2.5), PM(10) or NO(2) although adjustment for these pollutants strengthened the childhood O(3) associations
Impact of vaccines given during pregnancy on the offspring of women consulting a travel clinic: a longitudinal study (Publications)
range of 1 to 10 years. Rates of premature births were 5.7% in both groups; congenital abnormalities were 1.9% in the vaccinated cohort versus 5.7% in the nonvaccinated one; children took their first steps [...] steps at a median age of 12 months in both cohorts; among schoolchildren, 5% of the vaccinated cohort versus 7.7% of the nonvaccinated attended a lower level or a specialized school. CONCLUSION: In this
Response of Kampuchean strains of <em>Plasmodium falciparum</em> to antimalarials: in-vivo assessment of quinine and quinine plus tetracycline;... (Publications)
asexual parasites per microliter of blood. With a dosage of 1.5 g quinine base daily for 10 days the average parasite clearance time was 5.6 days, and the average duration of fever 3.4 days. The in-vivo [...] averaged 11,393 asexual parasites per microliter of blood. The average parasite clearance time was 5.9 days, and the average duration of fever was 3.8 days. After 7 days of treatment, 81.8% of patients
Alkamides from <em>Anacyclus pyrethrum</em> L. and their <em>in vitro</em> antiprotozoal activity (Publications)
isolated as an inseparable mixture (1:4). Compounds 3, 4, and 5 were isolated from Anacycluspyrethrum L. for the first time. While compounds 4 and 5 were previously known from the genus Achillea, compound 3 [...] deca-2E,4E-dienoic acid 2-phenylethylamide (4), undeca-2E,4E-dien-8,10-diynoic acid isopentylamide (5), tetradeca-2E,4E,12Z-trien-8,10-diynoic acid isobutylamide (6), and dodeca-2E,4E-dien acid 4-hydro
Étude du biais dû aux non-répondants dans une étude épidemiologique (SAPALDIA) (Publications)
smoking is similar in R and NR except a higher frequency of wheezing during the last 12 month (R: 12.5%, NR: 5.6%, p = 0.03). The level of carbon monoxide in expired air is higher in NR (17.6 ppm) that in R [...] and R (24.8 ppm) among current smokers (p < 0.01). The main reasons for refusal are lack of time (27.5%), lack of interest for medical study (22.6%), fear of health professionals (18.3%) or the existence
Impact of the warm summer 2015 on emergency hospital admissions in Switzerland (Publications)
warmest regions (Ticino [8.4%, 95% CI 5.1-11.7%] and the Lake Geneva region [4.8%, 95% CI 3.0-6.7%]) and among the elderly population aged > /=75 years (5.1%, 95% CI 3.7-6.5%). Increased EHA during days with
<em>Staphylococcus aureus</em> in nasal lavage and biopsy of patients with chronic rhinosinusitis (Publications)
and fluorescence in situ hybridization. To assess the effects of S. aureus positivity, interleukin-5 (IL-5), interferon-gamma, total immunoglobulin E (IgE), eotaxin, granulocyte-colony stimulating factor [...] groups (P = 0.3). Staphylococcus aureus small colony variants were not found. In nasal lavages, IL-5 and total IgE levels were higher in CRSNP(+) patients than in CRSNP(-) patients or controls (P < 0.05)