An intra-COVID-19 assessment of hand hygiene facility, policy and staff compliance in two hospitals in Sierra Leone: is there a difference between... (Publications)
capital city (17.0%) hospitals. The HH levels for the capital city and regional hospitals were 277.5 and 262.5 respectively. Despite the COVID-19 pandemic, there are still challenges with HH compliance in Sierra
In vitro antiprotozoal activities and cytotoxicity of some selected Cameroonian medicinal plants (Publications)
with IC50 values of 1.0 mu g/ml and 0.2 mu g/ml, respectively. Five extracts showed IC50 values below 5 mu g/ml against Leishmania donovani, with the methanolic seed extract of Harungana madagascarensis showing [...] extract of Albizia zygia showed the best ratio of cytotoxicity to antitrypanosomal activity (SIb = 22.5). (c) 2006 Elsevier Ireland Ltd. All rights reserved
<em>Plasmodium vivax</em> and mixed infections are associated with severe malaria in children: a prospective cohort study from Papua New Guinea (Publications)
anaemia [haemoglobin < 5 g/dl]). Out of 17,201 presumptive malaria cases, 9,537 (55%) had a confirmed Plasmodium parasitaemia. Among those, 6.2% (95% confidence interval [CI] 5.7%-6.8%) fulfilled the case
Cord blood allergen-specific IgE is associated with reduced IFN-gamma production by cord blood cells: The Protection against Allergy-Study in Rural... (Publications)
mothers, and 835 fathers. Supernatants from stimulated CB cells were assessed for the production of IL-5, IFN-gamma, IL-10, and TNF-alpha. RESULTS: Allergen-specific IgE antibodies were detectable in 23.9% [...] soybean allergen. Fetal IgE correlated negatively with the level of IFN-gamma production, but not with IL-5 and IL-10. CONCLUSION: Allergen-specific IgE antibodies most probably of fetal origin are detectable
Antitrypanosomal isoflavan quinones from <em>Abrus precatorius</em> (Publications)
NOESY) spectroscopy. Abruquinones J (1), K (2), and L (3) were new, while abruquinones A (4) and D (5) were known from the first batch of plant material. The absolute configuration of compounds 1 to 3 was [...] comparison of electronic circular dichroism (ECD) spectra with calculated ECD data. Compounds 2 to 5 showed high in vitro activity against T. b. rhodesiense (IC50 of 0.01, 0.02, 0.02 and 0.01muM, respectively)
Men benefit more from midlife leisure-time physical activity than women regarding the development of late-life disability - results from the KORA-age... (Publications)
of physical activity and disability. RESULTS: We analysed 3333 persons with a mean follow-up of 18±5.5years. Using hurdle models, moderate activity and high activity had a protective effect on the occurrence
Rapid and non-destructive detection and identification of two strains of <em>Wolbachia</em> in <em>Aedes aegypti</em> by near-infrared spectroscopy (Publications)
males infected with wMelPop from uninfected wild type samples with an accuracy of 96% (N = 299) and 87.5% (N = 377), respectively. Similarly, females and males infected with wMel were differentiated from [...] and wMel transinfected females with an accuracy of 96.6% (N = 442) and males with an accuracy of 84.5% (N = 443). This non-destructive technique is faster than the standard polymerase chain reaction diagnostic
Antiplasmodial and antitrypanosomal activity of tanshinone-type diterpenoids from <em>Salvia miltiorrhiza</em> (Publications)
tanshinone II a ( 2), 1,2 dihydrotanshinquinone ( 3), methylenetanshinquinone ( 4), 1-oxomiltirone ( 5), 11-hydroxymiltiodiol ( 6), tanshinone I ( 7), methyltanshinonate ( 8), and cryptotanshinone ( 9). [...] selectivity indices (SI) from 0.3 to 1.9. IC (50)s against T. BRUCEI RHODESIENSE STIB 900 were from 0.5 microM ( 1, 4) to over 30 microM, and 4 showed the greatest selective activity with an SI of 24
Abietane diterpenoids from <em>Salvia sahendica</em> - antiprotozoal activity and determination of their absolute configurations (Publications)
microM to over 32.3 microM against T. brucei rhodesiense. The cytotoxic IC50 values ranged from 0.5-15.5 microM. Selectivity indices for P. falciparum were 0.1 to 18.2, and 0.1 to 1.2 for T. brucei rhodesiense
Cord blood cytokines are modulated by maternal farming activities and consumption of farm dairy products during pregnancy: the PASTURE Study (Publications)
of IFN-gamma, TNF-alpha, IL-5, IL-10, and IL-12. RESULTS: Significantly higher levels of IFN-gamma and TNF-alpha in farm compared with nonfarm children were found, whereas IL-5, IL-10, and IL-12 levels did
