Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis (Publications)
not other PM metrics (PM2.5, coarse fraction of PM, PM absorbance), was associated with a lower level of FEV1 (-44.6 mL, 95% CI -85.4- -3.8) and FVC (-59.0 mL, 95% CI -112.3- -5.6). The associations were
Simulation of population-based commuter exposure to NO2 using different air pollution models (Publications)
range: 21-61) than with a dispersion model with a lower resolution (39 ± 5 µg m-3; range: 24-51), and a land use regression model (41 ± 5 µg m-3; range: 24-54). Highest median cumulative exposures were calculated
Development and validation of an enantioselective LM-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in... (Publications)
and concentrated on a C-18 trapping column. The analytical range for each PZQ enantiomer was 0.01-2.5µg/mL, and 0.1-25µg/mL for the metabolite. The method met the requirements regarding precision (±15% [...] pharmacokinetic studies. Moreover, the enantioselective separation was achieved with a run time of 11.5min and a simple sample processing method.
Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey (Publications)
participate (n=901). FINDINGS: Exposure of children younger than 1 year, compared with those aged 1-5 years, to stables and consumption of farm milk was associated with lower frequencies of asthma (1% 3/218 [...] independent from effect on atopic sensitisation. Continual long-term exposure to stables until age 5 years was associated with the lowest frequencies of asthma (0.8% 1/122), hay fever (0.8% 1), and atopic
Psychiatric disorders, suicidality, and personality among young men by sexual orientation (Publications)
statistical significance, and the odds ratio for suicide attempt was halved (OR=5.10, 95% CI 2.57-10.1; AOR=2.42, 95% CI 1.16-5.02). There are noteworthy differences in personality traits by sexual orientation
A worldwide map of <em>Plasmodium falciparum</em> K13-propeller polymorphisms (Publications)
m in 14,037 samples collected in 59 countries in which malaria is endemic. Most of the samples (84.5%) were obtained from patients who were treated at sentinel sites used for nationwide surveillance of [...] mutations, which showed marked geographic disparity in their frequency and distribution. In Asia, 36.5% of the K13 mutations were distributed within two areas--one in Cambodia, Vietnam, and Laos and the
Validation of self-reported figural drawing scales against anthropometric measurements in adults (Publications)
scales for identifying overweight or obese individuals with a correct detection rate were 4 and 5 in women, and 5 and 6 in men, respectively. The prediction model explained 74 % of the variance among women
Water quality, sanitation, and hygiene conditions in schools and households in Dolakha and Ramechhap districts, Nepal: results from a cross-sectional... (Publications)
school drinking water source samples and 76.9% point-of-use samples (water bottles) at schools, 39.5% water source samples in the community, and 27.4% point-of-use samples at household levels were contaminated [...] t coliforms. The values of water samples for pH (6.8-7.6), free and total residual chlorine (0.1-0.5 mg/L), mean lead concentration (0.01 mg/L), and mean arsenic concentration (0.05 mg/L) were within national
Allergic disease and atopic sensitization in children in relation to measles vaccination and measles infection (Publications)
Anthroposophic Lifestyle study, conducted in 5 European countries (Austria, Germany, the Netherlands, Sweden, and Switzerland). The children were between 5 and 13 years of age and represented farm children
Leishmanicidal cycloartane-type triterpene glycosides from <em>Astragalus oleifolius</em> (Publications)
Three known cycloartane glycosides cyclocanthoside E (3), astragaloside II (4) and astragaloside IV (5) were also isolated and characterized. All five compounds were evaluated for in vitro trypanocidal, [...] activities as well as their cytotoxic potential on primary mammalian (L6) cells. Except for the compound 5, all compounds showed notable growth inhibitory activity against Leishmania donovani with IC50 values
