Antiprotozoal, antitubercular and cytotoxic potential of cyanobacterial (blue-green algal) extracts from Ireland (Publications)
showed significant activity against T. b. rhodesiense (IC50 values 2.0 and 3.5 microg/mL) and P. falciparum (IC50s 7.4 and 5.8 microg/mL), with low toxicity. This trend was also true for R. biasolettiana
Brucellosis and bovine tuberculosis prevalence in livestock from pastoralist communities adjacent to Awash National Park, Ethiopia (Publications)
enzyme linked immunoassay for brucellosis, 4.8% (95%CI: 1.2-17.1%) of cattle and 22.8% (95%CI: 5.98-29.5%) of goats were reactors. Highest individual prevalence of both diseases was found in Afar settlements
How to evaluate health-related quality of life and its association with medication adherence in pulmonary tuberculosis - designing a prospective... (Publications)
d.) measures for HRQOL and adherence and to generate an endpoint model. Two generic (SF-12 and EQ-5D-5L), one disease-specific (St. George's Respiratory Questionnaire) and one condition-specific (Hospital
Air pollution and lung function in the European Community Respiratory Health Survey (Publications)
particles (PM(2.5)) were measured in 2000/2001 using central monitors. RESULTS: Despite sufficient statistical power no significant associations were found between city-specific annual mean PM(2.5) and average
Discovery of dual function acridones as a new antimalarial chemotype (Publications)
administration, inexpensive synthesis and favourable physicochemical properties), our initial lead, T3.5 (3-chloro-6-(2-diethylamino-ethoxy)-10-(2-diethylamino-ethyl)-acridone), demonstrates unique synergistic [...] -like' chemosensitization to chloroquine and amodiaquine against quinoline-resistant parasites, T3.5 also results in an apparently mechanistically distinct synergism with quinine and with piperaquine.
Diarrhoea, vomiting and the role of milk consumption: perceived and identified risk in Bamako (Mali) (Publications)
toxi-infections with diarrhoea and vomiting as main clinical picture. A total of 131 schoolchildren between 5 and 20 years of age were interviewed by trained interviewers in schools in Bamako. A structured que [...] identified regular consumption of boiled milk [odds ratio(OR) = 4.38; 95% CI = 1.15-16.71], age between 5 and 10 years (OR vs. age group 11-15 years = 3.28; 95% CI = 1.09-9.85) and the existence of dry latrines
Changes in active and passive smoking in the European Community Respiratory Health Survey (Publications)
adjusted hazard risk ratio (HRR) or odds ratio (OR). The prevalence of active smoking declined by 5.9% (5.1-6.8) and exposure to passive smoking in nonsmokers declined by 18.4% (16.8-20.0). Subjects with
A worldwide map of <em>Plasmodium falciparum</em> K13-propeller polymorphisms (Publications)
m in 14,037 samples collected in 59 countries in which malaria is endemic. Most of the samples (84.5%) were obtained from patients who were treated at sentinel sites used for nationwide surveillance of [...] mutations, which showed marked geographic disparity in their frequency and distribution. In Asia, 36.5% of the K13 mutations were distributed within two areas--one in Cambodia, Vietnam, and Laos and the
Qualitative analysis of cultural formulation interview: findings and implications for revising the outline for cultural formulation (Publications)
Interview (CFI) for DSM-5 provided a tool enabling wider use of cultural formulation in clinical cultural assessment. Validation to justify the inclusion of the CFI in DSM-5 involved quantitative analysis
Correlates and outcomes of alcohol use after single solid organ transplantation: a systematic review and meta-analysis (Publications)
reported > /=5 times. RESULTS: Of the 5331 studies identified, 76 were included in this systematic review (93.3% on liver Tx; mean sample size 148.9 (SD=160.2); 71.9% male; mean age 48.9years (SD=6.5); mean