The activity of dispiro peroxides against <em>Fasciola hepatica</em> (Publications)
Dispiro 1,2,4-trioxanes and 1,2,4,5-tetraoxanes had superior efficacy against Fasciola hepatica than the corresponding ozonides (1,2,4-trioxolanes). For highest efficacy, spiroadamantane and carboxymethyl
The activity of dispiro peroxides against <em>Fasciola hepatica</em> (Publications)
Dispiro 1,2,4-trioxanes and 1,2,4,5-tetraoxanes had superior efficacy against Fasciola hepatica than the corresponding ozonides (1,2,4-trioxolanes). For highest efficacy, spiroadamantane and carboxymethyl
Effectiveness of four different interventions against <em>Schistosoma haematobium</em> in a seasonal transmission setting of Côte d'Ivoire: a cluster... (Publications)
compared to the standard treatment arm (0.6% vs 7.5%; odds ratio [OR] = 0.07, 95% confidence interval [CI] = .02 to .24). The prevalence in arms 2 and 4 was about 3.5%, which was not statistically significantly
TNFA-308 in Two International Population-Based Cohorts Shows Increased Risk for Asthma (Publications)
polymorphism was associated with increased asthma prevalence (odds ratio for the A allele=1.3, 95%CI 1.1-1.5) and with bronchial hyper-responsiveness (OR=1.2, 95%CI 1.0-1.3). No consistent association was found [...] meta-analysis of 17 studies showed an increased asthma risk of the TNFA-308 A allele (OR=1.3, 95%CI 1.2-1.5).The TNFA-308 polymorphism is associated with a moderately increased risk for asthma and bronchial
Gynaecologic and breast cancers in women living with HIV in South Africa: A record linkage study (Publications)
gynaecologic cancer with patient- and municipal-level characteristics. From 3 447 908 women and 10.5 million years of follow-up, we identified 11 384 incident and 7612 prevalent gynaecologic and breast [...] [CI]: 106-110), with the highest incidence observed for cervical cancer (70/1 00 000 pyears; 95% CI: 68.5-71.7). Low CD4 cell counts and high HIV RNA viral loads increased the risk of cervical and other HPV-related
Population pharmacokinetics of the antimalarial amodiaquine: a pooled analysis to optimize dosing (Publications)
amodiaquine and desethylamodiaquine reached 50% of adult maturation at 2.8 (95% CI: 1.5 - 3.7) and 3.9 (95% CI: 2.6 - 5.3) months after birth, assuming a baby born at term. Bioavailability was 22.4% (15.6
Pastoralism and resulting challenges for national parks in Afar, Ethiopia (Publications)
pastoral encroachment into parks. Among the pastoralists, 74.7% migrated with their livestock for a mean 3.5 months per year, during which time, 90% of respondents reported contact with other livestock herds, [...] the main threat caused by the presence of pastoralists, whereas diseases were only mentioned by 15.5%. Overall, park staff showed poor disease knowledge. They reported poor disease surveillance and no
Burden of chronic pain among adult pastoralists in Ethiopia: a cross-sectional household survey (Publications)
(95% CI: 10.8-25.7) of male and 34.7% (95% CI: 28.4-41.5) of female adult pastoralists. The prevalence of chronic pain increased with age from 5.4% (95% CI: 0.8-30.1; 18-34 years) to 27.1% (95% CI: 15
Diabetes prevalence and associated factors in the adult population aged 25–64 in the Humbo districts of Woliata Zone (Publications)
less than 0.05. Diabetes was found in 5.9% of the research participants (95 percent CI: 3.8–7.8). Age 45–54 (AOR = 4.80, 1.25, 18.32), physical inactivity (AOR = 5.33, 1.37, 20.72), family history of diabetes
The number of comorbidities as an important cofactor to ASA class in predicting postoperative outcome: an international multicentre cohort study (Publications)
enrolled patients, the mean number of comorbidities significantly increased from 1.5 in ASA I (95% CI, 1.1-1.9) to 10.5 in ASA IV (95% CI, 8.3-12.7) patients. Furthermore, independent of ASA class, pos
