A review of ambient air pollution exposure assessment methods in determining childhood respiratory health effects in children under five (Publications)
use regression modeling (n = 5). These studies assessed exposure and outcomes at different “windows of susceptibility”: antenatally/specific trimesters (n = 8), infancy (n = 5) and early childhood (n = 6)
Child hand contamination is associated with subsequent pediatric diarrhea in rural Democratic Republic of the Congo (REDUCE Program) (Publications)
enrolment and analysed for Escherichia coli. Caregiver reports of diarrhoea were obtained from children < 5 years at a 6-month follow-up. RESULTS: E.coli was detected in 73% of child and caregiver hand-rinse [...] observed putting in their mouths, 74% of stored water samples, and 40% of source water samples. Children < 5 years with E. coli on their hands had significantly higher odds of diarrhoea at the 6-month follow-up
Direct costs of schizophrenia in Italian community psychiatric services (Publications)
56.3% of the total cost, daycare centre days for between 11.3 and 35.5%, home visits for 7.8 to 16.4%, and day-hospital days for 5.4 to 32.8%. Antipsychotics and anxiolytics were the most prescribed drugs
Pharmacokinetics, <em>Trypanosoma brucei gambiense</em> efficacy and time of drug action of DB829, a preclinical candidate for treatment of second... (Publications)
against the T. b. rhodesiense STIB900 strain. A single dose of DB829 administered intraperitoneally (5 mg/kg) cured all mice infected with different T. b. gambiense strains. No cross-resistance was observed [...] dose of DB829 (20 mg/kg) administered intraperitoneally clears parasites from mouse blood within 2-5 days. In summary, DB829 is a promising preclinical candidate for the treatment of first and second stage
Health impact assessment of transport policies in Rotterdam: decrease of total traffic and increase of electric car use (Publications)
kilometers and a share of 50% electric-powered private vehicle kilometers) on particulate matter (PM2.5), elemental carbon (EC) and noise (engine noise and tyre noise) were assessed using Years of Life Lost [...] have marginal effects on air pollution, because already implemented traffic policies will reduce PM2.5 and EC by around 40% and 60% respectively, from 2010 to 2020. DISCUSSION: The evaluation of planned
Global investment targets for malaria control and elimination between 2016 and 2030 (Publications)
Results: Annual investments of $6.4 billion (95% uncertainty interval (UI $4.5-$9.0 billion)) by 2020, $7.7 billion (95% UI $5.4-$10.9 billion) by 2025 and $8.7 billion (95% UI $6.0-$12.3 billion) by 2030
Air pollution and childhood leukaemia: a nationwide case-control study in Italy (Publications)
length of main roads within 100 m) and estimates of pollutants concentrations (particulate matter -PM2.5 and PM10- and gases -NO2 and O3-) from national dispersion model and land use regression models. The [...] controls lived along busy roads, and the mean annual PM10 levels were 33.3 (SD=6.3) and 33.4 µg/m3 (SD=6.5), respectively. No association was found, and all ORs, independent of the method of assessment and the
Molecular characterization, toxin detection and resistance testing of human clinical <em>Clostridium difficile </em>isolates from Lebanon (Publications)
testing. Ribotype 014 (RT014, 16.8%) predominated, followed by RT002 (9.3%), RT106 (8.4%) and RT070 (6.5%). Binary toxin gene-positive isolates (RT023, RT078 and RT126) were rarely detected and RT027 was absent [...] small proportion of strains displayed resistance against moxifloxacin, rifampicin, and clarithromycin (5.6%, 1.9%, and 2.8%), respectively. The data indicate that the genetic strain composition of Lebanese
Physical activity and dual disease burden among South African primary schoolchildren from disadvantaged neighbourhoods (Publications)
VD phenotype burden in South African schoolchildren. 801 children (402 boys, 399 girls; mean age 9.5years) from eight schools from disadvantaged neighbourhoods were included. Data assessment took place [...] (physically active on 6-7days/week for at least 60min), who were active, but below recommended standards (2-5 physically active days/week), or who were insufficiently active on almost all days (0-1 physically active
A genome-wide association study on medulloblastoma (Publications)
associated with increased medulloblastoma risk (p < 1 x 10(-5)), but none were statistically significant after adjusting for multiple testing (p < 5 x 10(-8)). Thirteen of these variants were genotyped, whereas