Sanitation in urban areas may limit the spread of antimicrobial resistance via flies (Publications)
used to quantify an enteric 16S rRNA gene (i.e., specific to a cluster of phylotypes corresponding to 5% of the human fecal microflora), 28 ARGs, and Kirby Bauer Disk Diffusion of Enterobacteriaceae isolates [...] assess resistance to eleven clinically relevant antibiotics. The intervention was associated with a 1.5 log10 reduction (95% confidence interval: -0.73, -2.3) in the concentration of the enteric 16S gene
Physical activity and dual disease burden among South African primary schoolchildren from disadvantaged neighbourhoods (Publications)
VD phenotype burden in South African schoolchildren. 801 children (402 boys, 399 girls; mean age 9.5years) from eight schools from disadvantaged neighbourhoods were included. Data assessment took place [...] (physically active on 6-7days/week for at least 60min), who were active, but below recommended standards (2-5 physically active days/week), or who were insufficiently active on almost all days (0-1 physically active
Molecular characterization, toxin detection and resistance testing of human clinical <em>Clostridium difficile </em>isolates from Lebanon (Publications)
testing. Ribotype 014 (RT014, 16.8%) predominated, followed by RT002 (9.3%), RT106 (8.4%) and RT070 (6.5%). Binary toxin gene-positive isolates (RT023, RT078 and RT126) were rarely detected and RT027 was absent [...] small proportion of strains displayed resistance against moxifloxacin, rifampicin, and clarithromycin (5.6%, 1.9%, and 2.8%), respectively. The data indicate that the genetic strain composition of Lebanese
A genome-wide association study on medulloblastoma (Publications)
associated with increased medulloblastoma risk (p < 1 x 10(-5)), but none were statistically significant after adjusting for multiple testing (p < 5 x 10(-8)). Thirteen of these variants were genotyped, whereas
Multicountry distribution and characterization of extended-spectrum β-lactamase-associated gram-negative bacteria from bloodstream infections in... (Publications)
least one of the screened ESBL genes. Among specific Gram-negative isolates, 40 (45.5%) of 88 Klebsiella spp., 7 (5.7%) of 122 Escherichia coli, 6 (16.2%) of 37 Acinetobacter spp., and 2 (1.3%) of 159
Association between transportation noise and cardio-metabolic diseases: an update of the WHO meta-analysis (Publications)
Thirteen studies were included in the IHD meta-analysis, contributing 13 risk estimates for road traffic, 5 for aircraft and 3 for railway noise exposure. Only the result for road traffic noise reached statistical [...] significance (1.02 [1.00-1.04] per 10 dB Lden). For diabetes, 6 studies were included, contributing 5 risk estimates for road traffic, 3 for aircraft and 2 for railway noise exposure. Again, only the road
Investigating the drivers of the spatio-temporal patterns of genetic differences between <em>Plasmodium falciparum</em> malaria infections in Kilifi... (Publications)
geographic distance between parent and offspring malaria infections for the base model was 0.5 km (95% CI 0.3-1.5), for a distribution with 68% of distances shorter than the mean. Very short mean distances
Inhibition of <em>Leishmania donovani</em> transformation by hamster spleen homogenates and active human lymphocytes (Publications)
from one stage to the next includes morphological antigenic, physiological, and infectivity changes2–5.
In a randomized controlled trial of iron fortification, anthelmintic treatment, and intermittent preventive treatment of malaria for anemia control in... (Publications)
among school children. The study was a 6-mo, randomized, double-blind, controlled trial enrolling 5
Chloroquine-astemizole hybrids with potent in vitro and in vivo antiplasmodial activity (Publications)
astemizole. A variety of linkers were investigated to conjugate the two agents into one molecule. Compounds 5-8 possessed improved in vitro activity against a CQ-resistant strain of Plasmodium falciparum, and examples
