Prevalence of asthma-like symptoms with ageing (Publications)
the prevalence of 'wheeze' and 'wheeze in the absence of a cold' decreased (-2.4%, 95% CI -3.5 to -1.3%; -1.5%, 95% CI -2.4 to -0.6%, respectively) but the prevalence of asthma attacks, use of asthma medication
Bayesian spatio-temporal modeling of mortality in relation to malaria incidence in western Kenya (Publications)
positive association with malaria-specific mortality in young children (HR = 9.48; 5.11-37.94), however, in older children (5-14 years), it was associated with a reduction in malaria specific mortality (HR
Effectiveness and profitability of preventive veterinary interventions in controlling infectious diseases of ruminant livestock in sub-Saharan Africa:... (Publications)
livestock diseases. The effectiveness and/or profitability of antimicrobial treatment (n = 5), test and slaughter (n = 5), and use of lay animal health workers (n = 1) applied exclusively, were evaluated in
Immunogenicity and protective efficacy of radiation-attenuated and chemo-attenuated PfSPZ vaccines in Equatoguinean adults (Publications)
of three doses of 2.7 x 10(6) PfSPZ of PfSPZ Vaccine at 8-week intervals and three doses of 1.0 x 10(5) PfSPZ of PfSPZ-CVac at 4-week intervals with each arm randomized, double-blind, placebo-controlled [...] dose was 55% (8 of 13, P = 0.051) and at a median of 15 weeks after last PfSPZ Vaccine dose was 27% (5 of 15, P = 0.32). The higher VE in PfSPZ-CVac recipients of 55% with a 27-fold lower dose was likely
Impact of long-term exposure to ambient ozone on lung function over a course of 20 years (The ECRHS study): a prospective cohort study in adults (Publications)
8-h average ozone concentrations to individual residential addresses. Adjustments were made for PM(2.5), NO(2), and greenness. To capture the ozone-related change in spirometric parameters, our linear mixed [...] 86 mL/year (-3.73, -1.99) mL/year over the study period. Associations were robust after adjusting for PM(2.5), NO(2), and greenness. The associations were more pronounced in residents of northern Europe and i
Assessment of fecal calprotectin and fecal occult blood as point-of-care markers for soil-transmitted helminth attributable intestinal morbidity in a... (Publications)
infections) and 157 STH negative controls were tested for FC and FOB. Among all participants tested, 18.5% had > /= 50 microg/g FC concentration, while 14 (1.2%) were positive for FOB. No statistically significant [...] the > /= 50 microg/g FC category was significantly higher in the oldest age category compared to the 5-11 years group (OR: 3.31, 95% CrI: 1.62, 7.24). Too few participants were found positive for FOB to
Short-term effects of PM10, NO2, SO2 and O3 on cardio-respiratory mortality in Cape Town, South Africa, 2006-2015 (Publications)
(95% CI: 0.4–4.1%), 1.4% (95% CI: 0–2.8%) and 2.5% (95% CI: 0.2–4.8%), respectively. For RD, only NO2 showed a significant positive association with a 4.5% (95% CI: 1.4–7.6%) increase per IQR. In multi
The association between apparent temperature and hospital admissions for cardiovascular disease in Limpopo province, South Africa (Publications)
lag-structure for the cold effect was inconsistent. A proportion of 8.5% (95% Confidence Interval (CI): 3.1%, 13.7%) and 1.1% (95% CI: -1.4%, 3.5%) of the total CVD admissions was attributable to cold and warm
Cross-sectional study of nutritional intake among patients undergoing tuberculosis treatment along the Myanmar-Thailand border (Publications)
on based on historical patient records. Out of a total of 28 participants, 20 (71.4%) were men and 5 (17.9%) were co-infected with HIV. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome compared [...] patients supplementing their rations. Mean treatment length at time of survey was 20.7 weeks (95% CI: 16.5 to 24.8). A significantly higher proportion of women (8/8, 100%) met caloric requirements compared with
Pollen exposure is associated with risk of respiratory symptoms during the first year of life (Publications)
mixed models (GAMM). Effect modification by maternal atopy, infant's sex and air pollution (NO2 , PM2.5 ) was assessed with interaction terms. RESULTS: Per infant 37+/-2 (mean+/-SD) respiratory symptom scores [...] by maternal atopy and infant's sex, a complex crossover interaction between combined pollen and PM2.5 was found (p-Value 0.002). CONCLUSION: Even as early as during the first year of life, pollen exposure