HPLC-based activity profiling for antiplasmodial compounds in the traditional Indonesian medicinal plant <em>Carica papaya</em> L (Publications)
HPLC-MS and MPLC-ELSD. Structures were established by HR-ESI-MS and NMR spectroscopy. For compounds 5 and 7 absolute configuration was confirmed by comparison of experimental and calculated electronic circular [...] nicotiflorin. Five compounds isolated from the alkaloidal fraction were piperidine alkaloids. Compounds 5 and 6 were inactive carpamic acid and methyl carpamate, while three alkaloids 7-9 showed high antiplasmodial
Mental health litaracy and the experience of depression in a community sample of gay men (Publications)
greater susceptibility among gay men, yet men with MDD reported problems with love/relationship (32.5%) and work (28.9%) as the most common perceived causes of recent depression, and problems with love [...] such as a close friend (91.6%), relaxation exercises or meditation (84.4%), and physical activity (83.5%) as being helpful for the depression vignette. LIMITATIONS: No probes used for open questions, and
Standard genotyping overestimates transmission of <em>Mycobacterium tuberculosis</em> among immigrants in a low incidence country (Publications)
found weak evidence for an association between birth origin and transmission (aOR 2.2, 95% CI: 0.9-5.5, comparing Swiss-born patients to others). In conclusion, standard genotyping overestimated recent
Immunogenicity and protective efficacy of radiation-attenuated and chemo-attenuated PfSPZ vaccines in Equatoguinean adults (Publications)
of three doses of 2.7 x 10(6) PfSPZ of PfSPZ Vaccine at 8-week intervals and three doses of 1.0 x 10(5) PfSPZ of PfSPZ-CVac at 4-week intervals with each arm randomized, double-blind, placebo-controlled [...] dose was 55% (8 of 13, P = 0.051) and at a median of 15 weeks after last PfSPZ Vaccine dose was 27% (5 of 15, P = 0.32). The higher VE in PfSPZ-CVac recipients of 55% with a 27-fold lower dose was likely
Perceived illness drives participation in mass deworming campaigns in Laos (Publications)
(19/21). Most leaders (20/21) had a good knowledge on severe schistosomiasis though only a few of them (5/21) described its cause correctly. They knew little about the disease consequences of liver fluke (3/21) [...] fish (100%), frequent physical contacts with Mekong River water (76.0%) and low number of latrines (14.5%). In conclusion, MDA is widely accepted in affected communities. Avoiding severe schistosomiasis was
A new nonpolar N-hydroxy imidazoline lead compound with improved activity in a murine model of late stage <em>Trypanosoma brucei brucei</em> infection... (Publications)
imidazoline analogues were the most effective in vivo with 4-((1-hydroxy-4,5-dihydro-1H-imidazol-2-yl)amino)-N-(4-((1-hydroxy-4,5-dihydro-1H -imidazol-2-yl)amino)phenyl)benzamide ( 14D: ) showing 100% cures
Hydrogen sulfide removal by <em>Thiobacillus thioparus</em> bacteria on seashell bed biofilters (Publications)
seashells with 63% porosity which contains Thiobacillus thioparus bacteria to the maximum height of 27.5 cm. By mixing phosphoric acid and sodium sulfide, H2S gas is released and its concentration is measured [...] 77-93% and the optimum temperature required for growing of the microorganisms is retained between 20.5-30 degrees C. After feeding the system for three weeks the efficiency started to increase so that by
Increasing blood flow increases kt/V(urea) and potassium removal but fails to improve phosphate removal (Publications)
removal only improved from 28.1 +/- 1.3 to 31.4 +/- 1.5 (p = 0.050) when Qb was increased from 200 to 250 ml/min but remained unchanged at 31.2 +/- 1.5 mMol (NS compared to phosphate removal at Qb = 250 ml/min)
Field efficacy of thermally expelled or live potted repellent plants against African malaria vectors in western Kenya (Publications)
significant repellency against Anopheles gambiae sensu lato Giles (Diptera: Culicidae) (81.5%An. arabiensis Patton and 18.5%An. gambiae sensu stricto Giles), the main vectors of malaria in Africa, with the highest
Reproducibility of pacing profiles in elite swimmers (Publications)
The level of both competitions for the analysis had to be at least national championships (7.7 +/- 5.4 wk apart). Standard error of measurement expressed as percentage of the subject's mean score (CV) [...] 0.9% and 2.6% in all finals. Split-time variability for finals and heats ranged between 0.9% and 2.5% (CL 0.3-4.9%). CONCLUSION: Pacing profiles are consistent between different competitions. Variability