Viral suppression after transition from nonnucleoside reverse transcriptase inhibitor- to dolutegravir-based antiretroviral therapy: a prospective... (Publications)
was 47 years [interquartile range (IQR): 38-56], and median (IQR) time since ART initiation was 5.9 (3.5-9.0) years. Among those with complete VL data, the rate of viral suppression to < 100 copies/mL
Cross-sectional study of nutritional intake among patients undergoing tuberculosis treatment along the Myanmar-Thailand border (Publications)
on based on historical patient records. Out of a total of 28 participants, 20 (71.4%) were men and 5 (17.9%) were co-infected with HIV. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome compared [...] patients supplementing their rations. Mean treatment length at time of survey was 20.7 weeks (95% CI: 16.5 to 24.8). A significantly higher proportion of women (8/8, 100%) met caloric requirements compared with
The role of extreme temperature in cause-specific acute cardiovascular mortality in Switzerland: a case-crossover study (Publications)
daily Tmean (24 degrees C) versus optimum temperature at 20 degrees C) and cold (OR = 1.15 [0.95-1.39], 5th percentile of daily Tmean (-3 degrees C) versus optimum temperature at 20 degrees C). Heat-related [...] with lower socio-economic position and education are at higher risk for heat-related mortality. PM2.5 increased the risk of heat-related mortality for heart failure, but not all-cause cardiovascular mortality
Efficacy and safety of tribendimidine, tribendimidine plus ivermectin, tribendimidine plus oxantel pamoate, and albendazole plus oxantel pamoate... (Publications)
non-inferior to albendazole plus oxantel pamoate (ERRs 99.5% [95% CI 99.2-99.7] vs 96.0% [93.9-97.4]; difference 3.52 percentage points [2.05-5.65]). Likewise, tribendimidine plus oxantel pamoate was n [...] non-inferior to albendazole plus oxantel pamoate (ERRs 96.5% [95% CI 94.9 to 97.6] vs 96.0% [93.9 to 97.4]; difference 0.48 percentage points [-1.61 to 2.88]). 3 h after treatment, headache (n=50 [8%])
Determining soil-transmitted helminth infection status and physical fitness of school-aged children (Publications)
STHs(3). The estimated global burden due to hookworm disease, ascariasis, and trichuriasis is 22.1, 10.5, and 6.4 million disability-adjusted life years (DALYs), respectively(4). Furthermore, an estimated [...] neglected STH species of global significance which arguably also causes a considerable public health impact(5,6). Multiple-species infections (i.e., different STHs harbored in a single individual) are common, and [...] sophisticated laboratory materials and is less time consuming than...
Acquired HIV drug resistance among adults living with HIV receiving first-line antiretroviral therapy in Rwanda: a cross-sectional nationally... (Publications)
4%) non-nucleoside reverse transcriptase inhibitor- (NNRTI), 291 (75.5%) nucleoside reverse transcriptase inhibitor- (NRTI) and 13 (3.5%) protease inhibitor (PI) resistance-associated mutations. The most [...] History of ever switching ART regimen was associated with NRTI resistance (aOR, 2.53 [95% CI: 1.198-5.356]; p = 0.016) and NNRTI resistance (aOR, 3.23 [95% CI: 1.435-7.278], p = 0.005). CONCLUSION: The
Determining soil-transmitted helminth infection status and physical fitness of school-aged children (Publications)
STHs(3). The estimated global burden due to hookworm disease, ascariasis, and trichuriasis is 22.1, 10.5, and 6.4 million disability-adjusted life years (DALYs), respectively(4). Furthermore, an estimated [...] neglected STH species of global significance which arguably also causes a considerable public health impact(5,6). Multiple-species infections (i.e., different STHs harbored in a single individual) are common, and [...] sophisticated laboratory materials and is less time consuming than...
Global, regional, and national burden of disorders affecting the nervous system, 1990-2021: a systematic analysis for the Global Burden of Disease... (Publications)
of DALYs attributed to these conditions decreased by 27·0% (21·5-32·4). Age-standardised prevalence was almost stable, with a change of 1·5% (0·7-2·4). The ten conditions with the highest age-standardised [...] DALYs in 2021 (443 million, 95% UI 378-521), affecting 3·40 billion (3·20-3·62) individuals (43·1%, 40·5-45·9 of the global population); global DALY counts attributed to these conditions increased by 18·2%
Acquired HIV drug resistance among adults living with HIV receiving first-line antiretroviral therapy in Rwanda: a cross-sectional nationally... (Publications)
4%) non-nucleoside reverse transcriptase inhibitor- (NNRTI), 291 (75.5%) nucleoside reverse transcriptase inhibitor- (NRTI) and 13 (3.5%) protease inhibitor (PI) resistance-associated mutations. The most [...] History of ever switching ART regimen was associated with NRTI resistance (aOR, 2.53 [95% CI: 1.198-5.356]; p = 0.016) and NNRTI resistance (aOR, 3.23 [95% CI: 1.435-7.278], p = 0.005). CONCLUSION: The
Efficacy and safety of tribendimidine, tribendimidine plus ivermectin, tribendimidine plus oxantel pamoate, and albendazole plus oxantel pamoate... (Publications)
non-inferior to albendazole plus oxantel pamoate (ERRs 99.5% [95% CI 99.2-99.7] vs 96.0% [93.9-97.4]; difference 3.52 percentage points [2.05-5.65]). Likewise, tribendimidine plus oxantel pamoate was n [...] non-inferior to albendazole plus oxantel pamoate (ERRs 96.5% [95% CI 94.9 to 97.6] vs 96.0% [93.9 to 97.4]; difference 0.48 percentage points [-1.61 to 2.88]). 3 h after treatment, headache (n=50 [8%])
