Searched for 5.

1. Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents (Publications)

   Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents

   Relevance:

   strains of the malarial parasite Plasmodium falciparum. Most of these derivatives showed a 4-49 and 5-17-fold increase in activity against NF54 and KI strains, respectively, as compared to FA and had a

2. Long term exposure to ambient air pollution and incidence of acute coronary events: prospective cohort study and meta-analysis in 11 European cohorts... (Publications)

   Long term exposure to ambient air pollution and incidence of acute coronary events: prospective cohort study and meta-analysis in 11 European cohorts from the ESCAPE Project

   Relevance:

   Italy. PARTICIPANTS: 100 166 people were enrolled from 1997 to 2007 and followed for an average of 11.5 years. Participants were free from previous coronary events at baseline. MAIN OUTCOME MEASURES: Modelled

3. Non-Ionising Radiation (Page)

   Non-Ionising Radiation

   Relevance:
   https://www.swisstph.ch/en/topics/environment-and-health/non-ionising-radiation

   Electromagnetic Fields and Planetary Health With the advent of the fifth generation of wireless technology (5G), a new wave of communication enhancements is emerging, including novel reception and transmission [...] You are welcome to contribute to the project as a citizen! Read more ETAIN Webinar Series GOLIAT - 5G Exposure, Causal Effects, and Risk Perception through Citizen Engagement The introduction of new c [...] potential health effects between two highly RF-EMF exposed groups, young...

4. A novel electronic algorithm using host biomarker point-of-care tests for the management of febrile illnesses in Tanzanian children (e-POCT): a... (Publications)

   A novel electronic algorithm using host biomarker point-of-care tests for the management of febrile illnesses in Tanzanian children (e-POCT): a randomized, controlled non-inferiority trial

   Relevance:

   in the e-POCT arm compared with 1.5% in the ALMANACH arm (RR 0.42, 95% CI 0.20, 0.87, p = 0.02). The proportion of antibiotic prescriptions was substantially lower, 11.5% compared to 29.7% (RR 0.39, 95% [...] with 4.1% (65/1,583) in the ALMANACH arm (risk difference of clinical failure -1.7, 95% CI -3.0, -0.5), meeting the prespecified criterion for non-inferiority. In a non-prespecified superiority analysis [...] to routine care (RR 0.51, 95% CI 0.31, 0.84, p = 0.007) and lowered antibiotic...

5. A novel electronic algorithm using host biomarker point-of-care tests for the management of febrile illnesses in Tanzanian children (e-POCT): a... (Publications)

   A novel electronic algorithm using host biomarker point-of-care tests for the management of febrile illnesses in Tanzanian children (e-POCT): a randomized, controlled non-inferiority trial

   Relevance:

   in the e-POCT arm compared with 1.5% in the ALMANACH arm (RR 0.42, 95% CI 0.20, 0.87, p = 0.02). The proportion of antibiotic prescriptions was substantially lower, 11.5% compared to 29.7% (RR 0.39, 95% [...] with 4.1% (65/1,583) in the ALMANACH arm (risk difference of clinical failure -1.7, 95% CI -3.0, -0.5), meeting the prespecified criterion for non-inferiority. In a non-prespecified superiority analysis [...] to routine care (RR 0.51, 95% CI 0.31, 0.84, p = 0.007) and lowered antibiotic...

6. Identification of a potential antimalarial drug candidate from a series of 2-aminopyrazines by optimization of aqueous solubility and potency across... (Publications)

   Identification of a potential antimalarial drug candidate from a series of 2-aminopyrazines by optimization of aqueous solubility and potency across the parasite life cycle

   Relevance:

   Introduction of water-solubilizing groups on the 5-phenyl ring of a 2-aminopyrazine series led to the identification of highly potent compounds against the blood life-cycle stage of the human malaria parasite

7. Vaccines for enteric diseases: update on recent developments (Publications)

   Vaccines for enteric diseases: update on recent developments

   Relevance:

   The 5th International Conference on Vaccines for Enteric Diseases (VED) attracted more than 250 delegates, mainly from industrialized countries. A total of 56 papers were presented and 46 posters were

8. Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian <em>Aplidium scabellum</em> (Publications)

   Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian <em>Aplidium scabellum</em>

   Relevance:

   y-1,4-hydroquinone-4-sulfate (1) and a family of pseudodimeric meroterpenoids scabellones A (2)-D (5). The benzo[c]chromene-7,10-dione scaffold contained within scabellones A-D is particularly rare among

9. Epidemiology of community-onset bloodstream infections in Bouaké, central Côte d'Ivoire (Publications)

   Epidemiology of community-onset bloodstream infections in Bouaké, central Côte d'Ivoire

   Relevance:

   Côte d'Ivoire, to determine the aetiology of community-onset BSI. The prevalence of bacteraemia was 22.5%, with children being most commonly affected. Enterobacteriaceae (predominantly Klebsiella pneumoniae

10. Epidemiology of community-onset bloodstream infections in Bouaké, central Côte d'Ivoire (Publications)

    Epidemiology of community-onset bloodstream infections in Bouaké, central Côte d'Ivoire

    Relevance:

    Côte d'Ivoire, to determine the aetiology of community-onset BSI. The prevalence of bacteraemia was 22.5%, with children being most commonly affected. Enterobacteriaceae (predominantly Klebsiella pneumoniae