Population genetic structure and hybridization of schistosomes in schoolchildren in Côte d’Ivoire (Publications)
identified 15 S. haematobium sequences (45.5%) belonging to seven haplotypes and 18 S. bovis sequences (54.5%) belonging to 12 haplotypes. Of 40 ITS2 sequences analysed, 77.5% were assigned to pure S. haematobium [...] haematobium, 10.0% to pure S. bovis and 12.5% to S. haematobium x S. bovis hybrids. The literature review elucidated that few methods are available for the population genetics of S. haematobium. Variable genetic
Novel 4-[4-(4-methylpiperazin-1-yl)phenyl]-6-arylpyrimidine derivatives and their antitrypanosomal activities against <em>T.brucei</em> (Publications)
with promising antitrypanosomal activity. In particular, 32 exhibits an in vitro EC(50) value of 0.5 µM against Trypanosoma brucei rhodesiense, and analogues 29, 30 and 33 show antitrypanosomal activities
Meta-analysis of exome array data identifies six novel genetic loci for lung function (Publications)
749 individuals of European ancestry from 23 studies, and 7,721 individuals of African Ancestry from 5 studies in the discovery stage, with follow-up in up to 111,556 independent individuals. Results: We
Exposure to radio-frequency electromagnetic fields from broadcast transmitters and risk of childhood cancer: a census-based cohort study (Publications)
conducted a time-to-event analysis including children under age 16 years living in Switzerland on December 5, 2000. Follow-up lasted until December 31, 2008. Second, all children living in Switzerland for some
The oxysterol and cholestenoic acid profile of mouse cerebrospinal fluid (Publications)
analysis technology. We found low levels of oxysterols and cholestenoic acids in CSF in the range of 5pg/mL-2.6ng/mL. As found in man, these concentrations are one to two orders of magnitude lower than in
Epilepsy in Laos: Knowledge, attitudes, and practices in the community (Publications)
consumption of pork meat by 10-21%, and a disease transmissible by contact with patients' saliva by 14.5% of patients and 44% of villagers (P
The changing epidemiology of malaria in Ifakara Town, southern Tanzania (Publications)
clinical data from a series of community- and hospital-based studies involving children up to the age of 5 years. There was a right shift and lowering in the age-specific parasite prevalence in the community-based
Novel nucleoside-based antimalarial compounds (Publications)
contrast to de novo biosynthesis that is utilized by the human host. A series of twenty-two 2-, 6- and 5'-modified adenosine ribonucleosides was synthesized, with the expectation that these compounds would
<em>Mycobacterium africanum</em> is associated with patient ethnicity in Ghana (Publications)
patients belonging to the Ewe ethnic group (adjusted odds ratio: 3.02; 95% confidence interval: 1.67-5.47, p
Efficacy and safety of the RTS,S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young... (Publications)
varying malaria transmission. METHODS AND FINDINGS: 6,537 infants aged 6-12 wk and 8,923 children aged 5-17 mo were randomized to receive three doses of RTS,S/AS01 or comparator vaccine. VE against clinical