Accounting for MOBility in AIR pollution exposure estimates in studies on long-term health effects. (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/accounting-for-mobility-in-air-pollution-exposure-estimates-in-studies-on-long-term-health-effects
existing air pollution exposure models, and will include these traffic-related pollutants: NO2, BC, PM2.5, PM2.5 elemental composition and UFP. These existing models will be enhanced to produce long-term hourly
Comparison of a new IgG-EIA for the detection of anti-plasmodium antibodies with two currently used assays (Publications)
with the ELISA from EUROIMMUN and the routine test used at the respec-tive centre. Thirty-four of 595 (5.7%) tested blood samples from centre 1 and 49 of 501 (9.8%) tested blood samples from centre 2 showed [...] 12 inconclusive results), indicating an anti-Plasmodium antibody prevalence in blood donations of 1.5%. From these 16 reactive samples, 13 were also detected by the index test, resulting in an assay sensitivity
Integrated human-animal sero-surveillance of Brucellosis in the pastoral Afar and Somali regions of Ethiopia (Publications)
prevalence was 48.3% in Afar and 34.9% in SRS (ranging from 0.0 to 74.5% at woreda level). 68.4% of all households in Afar and 57.5% of households in SRS had at least one animal reactor. Overall, 4.1% of
Epidemiology of <em>Mycobacterium tuberculosis</em> lineages and strain clustering within urban and peri-urban settings in Ethiopia (Publications)
isolates with shared patterns (n = 200/258) suggested a substantial rate of overall clustering (77.5%). After adjusting for the effect of geographical variations, clustering rate was significantly lower [...] were more likely to be associated with TBLN [3.47 (1.45, 8.29)] and TB-HIV co-infection [2.84 (1.61, 5.55)]. CONCLUSION: Despite the observed difference in strain diversity and geographical distribution
Artemisinin-based combination therapy does not measurably reduce human infectiousness to vectors in a setting of intense malaria transmission (Publications)
increased oocyst prevalence (OR [95%CI] = 3.9 [2.9-5.3], p < 0.001), but had no consistent effect on sporozoite prevalence (OR [95%CI] = 0.9 [0.7-1.2], p = 0.5). The estimated infectiousness of the human population
First insights into the phylogenetic diversity of <em>Mycobacterium tuberculosis</em> in Nepal (Publications)
(Euro-American lineage) with 41 (15.7%) isolates, and Lineage 1 (Indo-Oceanic lineage) with 30 isolates (11.5%). Based on spoligotyping, we found 45 different spoligotyping patterns that were previously described [...] confidence interval [95% CI] 1.42-4.67, p = 0.002), and any drug resistance (aOR 2.79; 95% CI 1.43-5.45; p = 0.002). We found no evidence for an association of Lineage 2 with age or BCG vaccination status
Chemometric analysis of biofluids from mice experimentally infected with <em>Schistosoma mansoni</em> (Publications)
sequence of metabolic events in urine, plasma and faecal water. METHODS: Ten female NMRI mice, aged 5 weeks, were infected with 80 S. mansoni cercariae each. Ten age- and sex-matched mice remained uninfected [...] composition and therefore only five metabolites were found discriminatory of infected mice, of which 5-aminovalerate was the most stable and showed a positive correlation with urinary PAG. CONCLUSIONS: The
Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood (Publications)
in life, such as regulatory T (Treg) cells. OBJECTIVE: We sought to assess whether Treg cells from 4.5-year-old children from the Protection against Allergy: Study in Rural Environments birth cohort study [...] CONCLUSIONS: Farm milk exposure was associated with increased Treg cell numbers on stimulation in 4.5-year-old children and might induce a regulatory phenotype early in life, potentially contributing to
Screening mammographies in Switzerland: what makes female and male physicians prescribe them? (Publications)
es more often than their colleagues from the German-speaking part (odds ratio OR 2.5; 95% confidence interval CI 1.5-4.2). Clinical practice in obstetrics/gynaecology (OR 2.4; CI 1.3-4.2) and a self-reported
Sensory modulation of voluntary and TMS-induced activation in hand muscles (Publications)
noxious D2 and digit V (D5) stimulation. Then, transcranial magnetic stimulation (TMS) was used to evoke MEPs in the same hand muscles at rest-conditioned by equal noxious D2 or D5 stimulation and individually