Limonoid orthoacetates and antiprotozoal compounds from the roots of<em> Pseudocedrela kotschyi</em> (Publications)
(1-3), named kotschyins A-C, and the known compounds 7-deacetylgedunin (4) and 7-deacetyl-7-oxogedunin (5). The structures of 1-3 were elucidated by analytical methods including 1D- and 2D-NMR spectroscopy
Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase (Publications)
We report the discovery of novel uracil-based acyclic compounds as inhibitors of deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase), an enzyme involved in nucleotide metabolism that has been identified
Training in flexible intensive insulin therapy improves quality of life, decreases the risk of hypoglycaemia and ameliorates poor metabolic control in... (Publications)
METHODS: We prospectively followed 45 type 1 diabetic patients of our outpatient clinic participating in 5 consecutive FIT teaching courses at the University Hospital of Basel. These courses consist of 7 weekly
Synthesis and antiprotozoal activity of pyridyl analogues of pentamidine (Publications)
A series of novel pyridyl analogues 1-18 of antiprotozoal drug 1,5-bis(4-amidinophenoxy)pentane (pentamidine) has been synthesized and tested for in vitro activities against Trypanosoma brucei rhodesiense
Diagnosis of <em>Opisthorchis viverrini</em> infection with handheld light microscopy in Lao People's Democratic Republic (Publications)
collected from 104 individuals, handheld microscopy revealed a sensitivity of 70.6% and a specificity of 89.5% for O. viverrini infection. Pearson's correlation for quantitative fecal egg counts between the two
Cinnamoylphenethyl amides from <em>Polygonum hyrcanicum</em> possess anti-trypanosomal activity (Publications)
but less active compounds, such as cannabisin B (2), tyrosol (3), p-coumaric acid (4), ferulic acid (5), and N-cis-feruloyltyramine (6) were also identified, along with N-trans-3,4-dimethoxycinnamoyldopamine
RF exposure survey of children and adults: first results from Slovenia (Publications)
never been conducted. Within the FP-7 funded project Geronimo a personal RF exposure measurements in 5 European countries are conducted following a common measurement protocol. First measurements from 49
Current status of schistosomiasis and soil-transmitted helminthiasis in Beyla and Macenta Prefectures, Forest Guinea (Publications)
(epg) for Schistosoma mansoni, 21.0% and 17.8 eggs per 10ml of urine for S. haematobium, 51.2% and 507.5 epg for hookworm, 8.1% and 89.1 epg for Ascaris lumbricoides and 2.4% and 16.7 epg for Trichuris trichiura
Sequence and expression of a gene from <em>Theileria annulata</em> coding for a 70-kilodalton heat-shock protein (Publications)
protein strongly homologous to hsp 70 from other organisms. Using this DNA as a probe, a homologous 2.5-kb RNA species was detected in sporozoites, piroplasms and a macroschizont-infected cell line, showing
Health-related quality of life measured by the SF12 in working populations: associations with psychosocial work characteristics (Publications)
to 13%, accounting for demographics, socioeconomic status, body mass index, and medical condition (5th model). Including health behavior and personality factors (full model), R2 change for work characteristics