<em>Schistosoma haematobium</em> egg excretion does not increase after exercise: implications for diagnostic testing (Publications)
positivity for S. haematobium (25.7% versus 23.0%, P = 0.31) and mean egg counts (10.2 eggs/10 mL versus 8.5 eggs/10 mL, P = 0.45) did not differ. Exercise before urine collection does not appear to increase S
Synthesis of jacaranone-derived nitrogenous cyclohexadienones and their antiproliferative and antiprotozoal activities (Publications)
CCRF-CEM leukemia, HCT-116 colon cancer, U251 glioblastoma, and, in addition, non-tumorigenic MRC-5 lung fibroblasts. Antiproliferative activities at micromolar concentrations could be shown. Antiprotozoal
Investigating sulfoxide-to-sulfone conversion as a prodrug strategy for a phosphatidylinositol 4-kinas inhibitor in a humanized mouse model of malaria (Publications)
The in vivo antimalarial efficacies of two PI4K inhibitors, a 3,5-diaryl-2-aminopyrazine sulfoxide and its corresponding sulfone metabolite, were evaluated in the NOD-scid IL2Rgamma(null) (NSG) murine
Data on <em>Leptospira interrogans sv Pomona</em> infection in meat workers in New Zealand (Publications)
against Leptospira interrogans sv Pomona in Meat Workers in New Zealand" (Pittavino et al., 2017) [5]. A prospective cohort study was conducted in four sheep slaughtering abattoirs in New Zealand (NZ)
Present drugs and future perspectives in treating soil-transmitted helminthiasis (Publications)
(Ancylostoma duodenale and Necator americanus) are responsible for the infection of approximately 1.5 billion people worldwide, mostly in tropical and subtropical regions. Preventive chemotherapy is the
Reduced Efficacy of Anthelmintic Drugs (Page)
https://www.swisstph.ch/en/news/20170926-reduced-efficacy-of-anthelmintic-drugs
Reduced Efficacy of Anthelmintic Drugs 26.09.2017 Approximately 1.5 billion people worldwide are affected by soil-transmitted helminth infections. Efficacy of current treatments is decreasing, as indicated [...] September in the peer-reviewed journal BMJ. About soil-transmitted helminth infections Approximately 1.5 billion people are infected with at least one of the three types of soil-transmitted helminths: Ascaris
Diversity, Equity and Inclusion (Page)
https://www.swisstph.ch/en/about/careers/diversity-equity-and-inclusion
SDGs. The DEI Network aims to contribute to SDGs 3, 5, 10 and 17. Goals 3 - Ensure healthy lives and promote well-being for all at all ages Goals 5 - Achieve gender equality and empower all women and girls
Dynamic electronic decision trees to manage childhood illness (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/dynamic-electronic-decision-trees-to-manage-childhood-illness
Every year in low- and middle-income countries, more than 5 million children under the age of 5 years die from preventable illnesses due to poor clinical management at the primary health care level. In
Pregnancy-related morbidity and risk factors for fatal foetal outcomes in the Taabo health and demographic surveillance system, Côte d'Ivoire (Publications)
non-receipt of preventive treatment such as iron/folic acid supplementation (aOR = 3.15; 95% CI 1.71-5.80), only two doses of tetanus vaccination (aOR = 2.59; 95% CI 1.56-4.30), malaria during pregnancy [...] and delivery by caesarean section (aOR = 13.03; 95% CI 4.24-40.08) or by instrumental delivery (aOR = 5.05; 95% CI 1.50-16.96). Women who paid for delivery were at a significantly lower odds of a fatal foetal
Dengue fever in Dar es Salaam, Tanzania: clinical features and outcome in populations of black and non-black racial category (Publications)
2.9 versus 2.7 days; p = 0.01). Malaria coinfection was not significantly different between black (5%) and non-black (1.6%) patients (p = 0.06). The same proportion of patients in both group had secondary [...] Non-black race (adjusted OR 3.9; 95% CI 1.3-12) and previously known diabetes (adjusted OR 43; 95% CI 5.2-361) were independently associated with severe dengue. CONCLUSIONS: Although all patients were infected
