Complement factor D, albumin, and immunoglobulin G anti-band 3 protein antibodies mimic serum in promoting rosetting of malaria-infected red blood... (Publications)
Complement factor D alone induced 30 to 40% of de novo rosetting. Its effect was additive to that of 0.5 mg/ml albumin and to that of 15 ng/ml of naturally occurring antibodies to the anion transport protein
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans (Publications)
excellent in vivo efficacies in the acute mouse model of trypanosomiasis, curing 3/4 or 4/4 animals at 4 x 5 mg/kg. Diamidine 1 and di( N-isopropyl)amidine 45, administered at 4 x 1 mg/kg, exhibited potency comparable
The burden of hydrocele on men in northern Ghana (Publications)
with larger ones. The pain associated with adenolymphangitis (ADL) renders them inactive for up to 5 days. Complications of lymph scrotum and ridicule from community members were a problem. Unmarried men
Creating competent health-care specialists: the Swiss school of public health (Publications)
(the second most expensive worldwide) is fragmented into 26 cantonal authorities for a population of 7.5 million. Cantons differ in policy, legislation and structure. Health insurance is compulsory although
Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives (Publications)
against the chloroquine- and pyrimethamine-resistant K1 strain of P. falciparum (IC50 range, 0.17 to 5 microM). In addition, seven compounds displayed activity against intracellular T. cruzi amastigotes
Manadoperoxides, a new class of potent antitrypanosomal agents of marine origin (Publications)
sponge Plakortis cfr. lita afforded a library of endoperoxyketal polyketides, manadoperoxides B-K (3-5 and 7-13) and peroxyplakoric esters B(3) (6) and C (14). Eight of these metabolites are new compounds
Changing patterns of soil-transmitted helminthiases in Zanzibar in the context of national helminth control programs (Publications)
the prevalence of S. stercoralis, hookworm, A. lumbricoides, and T. trichiura decreased by 81.0%, 80.5%, 70.6%, and 48.6%, respectively. Infection intensities decreased by > 95% for all helminth species
Population hemoglobin mean and anemia prevalence in Papua New Guinea: new metrics for defining malaria endemicity? (Publications)
general population; 21,664 individuals from 156 different communities were surveyed. Altitude ranged from 5 to 2120 meters. In young children, correlations between altitude and parasite rate, population Hb mean
Growth of mature beech in relation to ozone and nitrogen deposition: an epidemiological approach (Publications)
better for maximum rather than average exposure values. Coefficients indicated growth changes of -22.5% (14.3-28.6 confidence interval) and -35.1% (17.8-47.3) respectively per 10 ppm hours. These changes
DNA replication fidelity in <em>Mycobacterium tuberculosis</em> is mediated by an ancestral prokaryotic proofreader (Publications)
DnaE1 itself encodes an editing function that proofreads DNA replication, mediated by an intrinsic 3'-5' exonuclease activity within its PHP domain. Inactivation of the DnaE1 PHP domain increases the mutation
