Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives (Publications)
against the chloroquine- and pyrimethamine-resistant K1 strain of P. falciparum (IC50 range, 0.17 to 5 microM). In addition, seven compounds displayed activity against intracellular T. cruzi amastigotes
Manadoperoxides, a new class of potent antitrypanosomal agents of marine origin (Publications)
sponge Plakortis cfr. lita afforded a library of endoperoxyketal polyketides, manadoperoxides B-K (3-5 and 7-13) and peroxyplakoric esters B(3) (6) and C (14). Eight of these metabolites are new compounds
Growth of mature beech in relation to ozone and nitrogen deposition: an epidemiological approach (Publications)
better for maximum rather than average exposure values. Coefficients indicated growth changes of -22.5% (14.3-28.6 confidence interval) and -35.1% (17.8-47.3) respectively per 10 ppm hours. These changes
The burden of hydrocele on men in northern Ghana (Publications)
with larger ones. The pain associated with adenolymphangitis (ADL) renders them inactive for up to 5 days. Complications of lymph scrotum and ridicule from community members were a problem. Unmarried men
Population hemoglobin mean and anemia prevalence in Papua New Guinea: new metrics for defining malaria endemicity? (Publications)
general population; 21,664 individuals from 156 different communities were surveyed. Altitude ranged from 5 to 2120 meters. In young children, correlations between altitude and parasite rate, population Hb mean
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans (Publications)
excellent in vivo efficacies in the acute mouse model of trypanosomiasis, curing 3/4 or 4/4 animals at 4 x 5 mg/kg. Diamidine 1 and di( N-isopropyl)amidine 45, administered at 4 x 1 mg/kg, exhibited potency comparable
Adiposity, fitness and metabolic risk in children: a cross-sectional and longitudinal study (Publications)
chronic inflammation and insulin resistance (IR) in school children. Methods. Eighty-three 1(st) and 5(th) grade children from a randomly selected control group of a physical activity intervention study
Rapid increase in the risk of heat-related mortality (Publications)
the climate of 2020. These return periods are projected to further shorten under warming levels of 1.5 °C and 2 °C, where heat-mortality extremes of the past climate will eventually become commonplace if
Contextual variation in young children's acquisition of social-emotional skills (Publications)
This study examined variation in the timing of 5,447 infants' and toddlers' reported acquisition of 12 basic social-emotional skills across and within 11 developing and developed country sites. Although
<em>Schistosoma mansoni</em> in schoolchildren in a Madagascan highland school assessed by PCR and sedimentation microscopy and Bayesian estimation of... (Publications)
Bayesian posterior estimate of the prevalence is 80.2%. Simple sedimentation technique misses about 4/5 of all PCR-confirmed infections and is insufficient to determine the prevalence of S. mansoni. A survey