Searched for 5.

1. "3 by 5" - Ein WHO/UNAIDS-Plan - können 3 Millionen Menschen bis Ende 2005 eine HIV-Therapie erhalten? (Publications)

   "3 by 5" - Ein WHO/UNAIDS-Plan - können 3 Millionen Menschen bis Ende 2005 eine HIV-Therapie erhalten?

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2. Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age (Publications)

   Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

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   than 2500 parasites per microliter, and the mean duration of follow-up was 7.9 months (range, 4.5 to 10.5). RESULTS: A total of 894 children were randomly assigned to receive the RTS,S/AS01E vaccine or [...] We evaluated the efficacy of RTS,S given with a more immunogenic adjuvant system (AS01E) in children 5 to 17 months of age, a target population for vaccine licensure. METHODS: We conducted a double-blind

3. Ancistrolikokine D, a 5,8'-coupled naphthylisoquinoline alkaloid, and related natural products from <em>Ancistrocladus likoko</em> (Publications)

   Ancistrolikokine D, a 5,8'-coupled naphthylisoquinoline alkaloid, and related natural products from <em>Ancistrocladus likoko</em>

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4. Ancistrolikokines A-C: new 5,8'-coupled naphthylisoquinoline alkaloids from <em>Ancistrocladus likoko</em> (Publications)

   Ancistrolikokines A-C: new 5,8'-coupled naphthylisoquinoline alkaloids from <em>Ancistrocladus likoko</em>

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5. Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the <em>Plasmodium falciparum</em> dUTPase (Publications)

   Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the <em>Plasmodium falciparum</em> dUTPase

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   Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) is a potential drug target for malaria. We previously reported some 5'-tritylated deoxyuridine analogues (both cyclic and acyclic) as selective

6. Efficacy and safety of CGP 56697 (artemether and benflumetol) compared with chloroquine to treat acute falciparum malaria in Tanzanian children aged... (Publications)

   Efficacy and safety of CGP 56697 (artemether and benflumetol) compared with chloroquine to treat acute falciparum malaria in Tanzanian children aged 1-5 years

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   88-97.5) for CGP 56697 and 35.4% (95% CI 25.9-45.8) for chloroquine. Using the same definition, the 14-day parasitological cure rates were 86.4% (95% CI 78.5-92.2) for CGP 56697 and 10.3% (95% CI 5.1-18 [...] A randomized, open trial involving 260 Tanzanian children, aged 1-5 years, with acute Plasmodium falciparum malaria was conducted to evaluate the efficacy of the combination antimalarial CGP 56697 (artemether

7. PM2.5 assessment in 21 European study centers of ECRHS II: Method and first winter results (Publications)

   PM2.5 assessment in 21 European study centers of ECRHS II: Method and first winter results

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   of 2.5 microm aerodynamic diameter (PM2.5) in the ECRHS II and to present the PM2.5 results from the winter period 2000-2001. Because PM2.5 is not routinely monitored in Europe, we measured PM2.5 mass [...] days per month for a year. Winter mean PM2.5 mass concentrations (November 2000-February 2001) varied substantially, with Iceland reporting the lowest value (5 microg/m3) and northern Italy the highest [...] highest (69 microg/m3). A standardized procedure appropriate for PM2.5 exposure...

8. PM2.5 and NO2 assessment in 21 European study centres of ECRHS II: annual means and seasonal differences (Publications)

   PM2.5 and NO2 assessment in 21 European study centres of ECRHS II: annual means and seasonal differences

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   health, in particular asthma and change of pulmonary function. Since PM2.5 is not routinely monitored in Europe, we measured PM2.5 concentrations in 21 participating centres to estimate 'background' exposure [...] values of PM2.5 were determined from measuring periods between June 2000 and November 2001. Sampling was conducted for 7 days per month for a year. Annual and winter mean concentrations of PM2.5 vary substantially [...] The range of PM2.5 mass concentrations obtained in ECRHS II is...

9. Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive 3,7-bis(dialkylamino)phenoxazin-5-ium derivatives (Publications)

   Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive 3,7-bis(dialkylamino)phenoxazin-5-ium derivatives

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10. Structure-activity relationship studies of orally active antimalarial 3,5-substituted 2-aminopyridines (Publications)

    Structure-activity relationship studies of orally active antimalarial 3,5-substituted 2-aminopyridines

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    potential cardiotoxicity liabilities identified with earlier frontrunner compounds, a number of new 3,5-diaryl-2-aminopyridine derivatives were synthesized. Several compounds exhibited potent antiplasmodial