Abietane-type diterpenoid amides with highly potent and selective activity against <em>Leishmania donovani</em> and <em>Trypanosoma cruzi</em> (Publications)
amastigotes residing in L6 cells with an IC50 value of 0.6 muM and high selectivity index of 58, being 3.5 times more potent than the reference compound benznidazole. The potent activity of this compound and
Quantitative evaluation of a handheld light microscope for field diagnosis of soil-transmitted helminth infection (Publications)
gram of stool (EPG). Mean egg counts were significantly higher with the conventional light microscope (5,190.0 EPG versus 2,385.8 EPG for Ascaris lumbricoides; 826.3 versus 455.7 for Trichuris trichiura; both
EPD in its twentieth year: towards complete promoter coverage of selected model organisms (Publications)
from release 73, from mass genome annotation projects. Subsets of promoter sequences with customized 5' and 3' extensions can be downloaded from the EPD website. The focus of current development efforts
Incidence of asthma and net change in symptoms in relation to changes in obesity (Publications)
never obese (hazard ratio 2.00, 95% confidence interval 1.25 to 3.20, excess net change 2.8%, 0.4 to 5.3%, per 10 years). The effect of being obese on net change in diagnosed asthma was greater in women
Stray dog population demographics in Jodhpur, India following a population control/rabies vaccination program (Publications)
declined (p 0.05) in 1 area, and remained stable in 1 area between 2005 and 2007. By 2007, 61.8-86.5% of the free-roaming dog population was surgically sterilized and vaccinated for rabies in the areas
Planning a family: priorities and concerns in rural Tanzania (Publications)
fertility survey using qualitative and quantitative techniques described a high fertility setting (TFR 5.8) in southern Tanzania where family planning use was 16%. Current use was influenced by rising parity
Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1<em>H</em>-1,2,3-triazoles (Publications)
Diimidazoline 60 exhibited antiplasmodial IC50 value of 0.6 W. Seven congeners administered at 4 x 5 mg/kg by the intraperitoneal route cured at least three out of four animals in the acute mouse model
Bovine tuberculosis in Ethiopian wildlife (Publications)
animals (23%) were positive for BTB by RT; acid-fast bacilli were cultured from 29 of 89 animals (32.5%). None of the positive cultures yielded mycobacteria from the Mycobacterium tuberculosis complex but
<em>Ascaris lumbricoides</em> egg die-off in an experimental excreta storage system and public health implication in Vietnam (Publications)
of viable A. lumbricoides eggs decreased gradually from 76.72 +/- 11.23% (mean +/- SD) to 8.26 +/- 5.20%. The storage time and the high pH value significantly increased the die-off of helminth eggs. Over
Sensitive and accurate quantification of human malaria parasites using droplet digital PCR (ddPCR) (Publications)
high (> 0.95) between qPCR and ddPCR. Quantification between technical replicates by ddPCR differed 1.5-1.7-fold, compared to 2.4-6.2-fold by qPCR. ddPCR facilitates parasite quantification for studies where