Changes in oral health over a 10-yr period in Switzerland (Publications)
The Swiss Health Surveys are conducted every 5 yr, and alternate surveys contain information on oral health. Worldwide the population is ageing and oral health is improving. The aim of this study was to
Rickettsial illnesses as important causes of febrile illness in Chittagong, Bangladesh (Publications)
and associated seasonality patterns. We diagnosed scrub typhus in 16.8% (70/416) and murine typhus in 5.8% (24/416) of patients; 2 patients had infections attributable to undifferentiated Rickettsia spp.
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets (Publications)
s.d. of the risk score ( approximately 6 alleles) (95% confidence interval) = 1.24 (1.20-1.27), P = 5.05 x 10-49), and we observed a 3.7-fold difference in COPD risk between individuals in the highest and
International workshop on insecticide resistance in vectors of arboviruses, December 2016, Rio de Janeiro, Brazil (Publications)
international workshop on Insecticide resistance in vectors of arboviruses held in Rio de Janeiro, Brazil, 5-8 December 2016. The primary aims of this workshop were to identify strategies for the development and
Malaria-anemia comorbidity prevalence as a measure of malaria-related deaths in sub-Saharan Africa (Publications)
geostatistical models. Mortality hazard obtained from malaria-anemia comorbidity prevalence was up to 3ยท5 times higher compared to the hazard related to Plasmodium parasitaemia only. Malaria parasite prevalence
Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1<em>H</em>-1,2,3-triazoles (Publications)
Diimidazoline 60 exhibited antiplasmodial IC50 value of 0.6 W. Seven congeners administered at 4 x 5 mg/kg by the intraperitoneal route cured at least three out of four animals in the acute mouse model
Contribution of influenza immunity and virosomal-formulated synthetic peptide to cellular immune responses in a phase I subunit malaria vaccine trial (Publications)
falciparum apical membrane antigen-1 (AMA-1) was observed with stimulation indices ranging from 2 to 4.5. All volunteers showed pre-existing IRIV specific cellular immunity assessed by ex vivo IFN-gamma ELISpot
A novel in vitro screening assay for trypanocidal activity using the fluorescent dye BCECF-AM (Publications)
developed for the screening of new compounds against African trypanosomes. 2',7'-Bis-(carboxyethyl)-5(6)-carboxyfluorescein-pentaacetoxymethyles ter (BCECF-AM), an esterase substrate, was used in the assay
EPD in its twentieth year: towards complete promoter coverage of selected model organisms (Publications)
from release 73, from mass genome annotation projects. Subsets of promoter sequences with customized 5' and 3' extensions can be downloaded from the EPD website. The focus of current development efforts
Quantitative evaluation of a handheld light microscope for field diagnosis of soil-transmitted helminth infection (Publications)
gram of stool (EPG). Mean egg counts were significantly higher with the conventional light microscope (5,190.0 EPG versus 2,385.8 EPG for Ascaris lumbricoides; 826.3 versus 455.7 for Trichuris trichiura; both