Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations (Publications)
studies from the International COPD Genetics Consortium. We identified 82 loci associated with P < 5 x 10(-8); 47 of these were previously described in association with either COPD or population-based
<em>Ascaris lumbricoides</em> egg die-off in an experimental excreta storage system and public health implication in Vietnam (Publications)
of viable A. lumbricoides eggs decreased gradually from 76.72 +/- 11.23% (mean +/- SD) to 8.26 +/- 5.20%. The storage time and the high pH value significantly increased the die-off of helminth eggs. Over
Sensitive and accurate quantification of human malaria parasites using droplet digital PCR (ddPCR) (Publications)
high (> 0.95) between qPCR and ddPCR. Quantification between technical replicates by ddPCR differed 1.5-1.7-fold, compared to 2.4-6.2-fold by qPCR. ddPCR facilitates parasite quantification for studies where
Contribution of influenza immunity and virosomal-formulated synthetic peptide to cellular immune responses in a phase I subunit malaria vaccine trial (Publications)
falciparum apical membrane antigen-1 (AMA-1) was observed with stimulation indices ranging from 2 to 4.5. All volunteers showed pre-existing IRIV specific cellular immunity assessed by ex vivo IFN-gamma ELISpot
The Mini-FLOTAC technique for the diagnosis of helminth and protozoan infections in humans and animals (Publications)
This protocol is an extension to: Nat. Protoc. 5, 503-515 (2010); doi: 10.1038/nprot.2009.235; published online 25 February 2010The FLOTAC is a sensitive, accurate, and precise technique for the diagnosis
Bovine tuberculosis in Ethiopian wildlife (Publications)
animals (23%) were positive for BTB by RT; acid-fast bacilli were cultured from 29 of 89 animals (32.5%). None of the positive cultures yielded mycobacteria from the Mycobacterium tuberculosis complex but
Rickettsial illnesses as important causes of febrile illness in Chittagong, Bangladesh (Publications)
and associated seasonality patterns. We diagnosed scrub typhus in 16.8% (70/416) and murine typhus in 5.8% (24/416) of patients; 2 patients had infections attributable to undifferentiated Rickettsia spp.
Changes in oral health over a 10-yr period in Switzerland (Publications)
The Swiss Health Surveys are conducted every 5 yr, and alternate surveys contain information on oral health. Worldwide the population is ageing and oral health is improving. The aim of this study was to
HIV infection functionally impairs <em>Mycobacterium tuberculosis</em>-specific CD4 and CD8 T-cell responses (Publications)
(n=15) or PTB (n=10). We showed that HIV infection significantly reduced the proportion of Th2 (IL-4/IL-5/IL-13) producing Mtb-specific CD4 T cells and IL-2 producing Mtb-specific CD4 and CD8 T cells in both
International workshop on insecticide resistance in vectors of arboviruses, December 2016, Rio de Janeiro, Brazil (Publications)
international workshop on Insecticide resistance in vectors of arboviruses held in Rio de Janeiro, Brazil, 5-8 December 2016. The primary aims of this workshop were to identify strategies for the development and