Diversity of human intestinal helminthiasis in Lao PDR (Publications)
trematodes included Phaneropsolus bonnei (22.7%), Prosthodendrium molenkampi (14.4%), Haplorchis pumilio (5.2%), Haplorchis yokogawai (3.1%) and Echinochasmus japonicus (3.1%). Co-infection with O. viverrini
Testing for <em>Chlamydia trachomatis</em>: time trends in positivity rates in the canton of Basel-Stadt, Switzerland (Publications)
SUMMARY National health statistics report a 2·5-fold increase in laboratory-confirmed Chlamydia trachomatis (CT) cases over the last decade in Switzerland where no CT screening programme exists. We obtained
Indole and benzimidazole bichalcophenes: synthesis, DNA binding and antiparasitic activity (Publications)
rhodesiense, a model that mimics the acute stage of African sleeping sickness, at a low dose of 4 x 5 mg/kg i.p. and hence 7c is more potent in vivo than pentamidine.
Epidemiology of paediatric meningitis in central Côte d'Ivoire after the implementation of <em>Haemophilus influenzae</em> type B vaccination (Publications)
with the most prevalent pathogens being Streptococcus pneumoniae (n=15) and Neisseria meningitidis (n=5). With the exception of neonates, these two bacteria were the most common agents in all age groups.
Five insights from the Global Burden of Disease Study 2019 (Publications)
trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3.5 billion estimates of health outcome and health system measures of interest for global, national, and
Longitudinal monitoring of SARS-CoV-2 RNA on high-touch surfaces in a community setting (Publications)
gas station). The estimated risk of infection from touching a contaminated surface was low (less than 5 in 10,000), suggesting fomites play a minimal role in SARS-CoV-2 community transmission. The weekly
New acyl derivatives of 3-aminofurazanes and their antiplasmodial activities (Publications)
efficiency) or determined experimentally (permeability) via a PAMPA. The N-(4-(3,4-diethoxyphenyl)-1,2,5-oxadiazol-3-yl)-3-(trifluoromethyl)benzamide possessed good physicochemical properties and showed high
Modelling the impact of COVID-19-related programme interruptions on visceral leishmaniasis in India (Publications)
estimated to range between 0 and 9 y. Highly endemic settings where control efforts have been ongoing for 5-8 y are most affected by an interruption, for which we identified a mitigation strategy to be most relevant
Genomic analyses of <em>Mycobacterium tuberculosis</em> from human lung resections reveal a high frequency of polyclonal infections (Publications)
the detection of multiple strains (40% of surgery cases) as opposed to just using a sputum sample (0-5% in the general population). We show that polyclonal infections often involve genetically distant strains
A recombinant blood-stage malaria vaccine reduces<em> Plasmodium falciparum</em> density and exerts selective pressure on parasite populations in a... (Publications)
oil-based adjuvant. A phase 1-2b double-blind, randomized, placebo-controlled trial in 120 children (5-9 years old) in Papua New Guinea demonstrated a 62% (95% confidence limits: 13%, 84%) reduction in parasite