Biological and epidemiological consequences of MTBC diversity (Publications)
factors. Different MTBC strains display different cellular and clinical phenotypes. Strains from Lineage 5 and Lineage 6 are metabolically different, grow slower, and are less virulent. Also, at least certain
Sero-prevalence and risk factors for leptospirosis in abattoir workers in New Zealand (Publications)
average sero-prevalence of 10%-31%, from the two deer abattoirs 17%-19% and the two beef abattoirs 5%. The strongest risk factor for sero-positivity in sheep and deer abattoirs was work position. In sheep
The influence of malaria control interventions and climate variability on changes in the geographical distribution of parasite prevalence in Kenya... (Publications)
indicators and climatic/environmental predictors of parasitaemia risk by age groups (6-59 months and 5-14 years). Parasitaemia risk and the number of infected children were predicted over a 1 × 1 km(2) grid
Building community health resilience and alleviating poverty through multi-sectoral cooperation for elimination of schistosomiasis in Cambodia and Lao... (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/building-community-health-resilience-and-alleviating-poverty-through-multi-sectoral-cooperation-for-elimination-of-schistosomiasis-in-cambodia-and-lao-peoples-democratic-republic
and operational research are designed to measure impacts and generate evidence of success; and target 5: All activities under the Project are implemented according to the proposal. Key activities proposed
Genomic analyses of <em>Mycobacterium tuberculosis</em> from human lung resections reveal a high frequency of polyclonal infections (Publications)
the detection of multiple strains (40% of surgery cases) as opposed to just using a sputum sample (0-5% in the general population). We show that polyclonal infections often involve genetically distant strains
New acyl derivatives of 3-aminofurazanes and their antiplasmodial activities (Publications)
efficiency) or determined experimentally (permeability) via a PAMPA. The N-(4-(3,4-diethoxyphenyl)-1,2,5-oxadiazol-3-yl)-3-(trifluoromethyl)benzamide possessed good physicochemical properties and showed high
Quantification of health benefits of the new Air Quality Guidelines of the World Health Organisation in Switzerland (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/quantification-of-health-benefits-of-the-new-air-quality-guidelines-of-the-world-health-organisation-in-switzerland
(including mortality and morbidity) of WHO AQG levels in Switzerland. The focus of the study is on PM2.5 and NO2 as air pollution indicators. The health benefits of WHO AQG values are compared for two different
Resistance Evaluation and Surveillance Initiative for Schistosomiasis Treatment (RESIST) (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/resistance-evaluation-and-surveillance-initiative-for-schistosomiasis-treatment-resist
possibility of interruption of transmission. However, a few hotspots with high prevalence of infection (5-10%) remain. This project is set in Pemba (Zanzibar, Tanzania), where we hypothesise that MDA-driven
The burden of disease in Greece, health loss, risk factors, and health financing, 2000-16: an analysis of the Global Burden of Disease Study 2016 (Publications)
correlation analysis. Findings All-age mortality in Greece increased from 944.5 (95% uncertainty interval [UI] 923.1-964.5) deaths per 100 000 in 2000 to 997.8 (975.4-1018) in 2010 and 1174.9 (1107.4-1243
Guide posts for investment in primary health care and projected resource needs in 67 low-income and middle-income countries: a modelling study (Publications)
$65. Overall health workforces would need to increase from 5.6 workers per 1000 population to 6.7 per 1000 population, delivering an average of 5.9 outpatient visits per capita per year. Increasing coverage