Resistance Evaluation and Surveillance Initiative for Schistosomiasis Treatment (RESIST) (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/resistance-evaluation-and-surveillance-initiative-for-schistosomiasis-treatment-resist
possibility of interruption of transmission. However, a few hotspots with high prevalence of infection (5-10%) remain. This project is set in Pemba (Zanzibar, Tanzania), where we hypothesise that MDA-driven
Quantification of health benefits of the new Air Quality Guidelines of the World Health Organisation in Switzerland (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/quantification-of-health-benefits-of-the-new-air-quality-guidelines-of-the-world-health-organisation-in-switzerland
(including mortality and morbidity) of WHO AQG levels in Switzerland. The focus of the study is on PM2.5 and NO2 as air pollution indicators. The health benefits of WHO AQG values are compared for two different
The burden of disease in Greece, health loss, risk factors, and health financing, 2000-16: an analysis of the Global Burden of Disease Study 2016 (Publications)
correlation analysis. Findings All-age mortality in Greece increased from 944.5 (95% uncertainty interval [UI] 923.1-964.5) deaths per 100 000 in 2000 to 997.8 (975.4-1018) in 2010 and 1174.9 (1107.4-1243
Guide posts for investment in primary health care and projected resource needs in 67 low-income and middle-income countries: a modelling study (Publications)
$65. Overall health workforces would need to increase from 5.6 workers per 1000 population to 6.7 per 1000 population, delivering an average of 5.9 outpatient visits per capita per year. Increasing coverage
How much will it cost to eradicate lymphatic filariasis? An analysis of the financial and economic costs of intensified efforts against lymphatic... (Publications)
(7.12bn-7.94bn), while the elimination scenario is projected to have an economic cost of 5.21 billion USD (4.91bn-5.45bn). Countries in the AFRO region will require the greatest investment to reach elimination
<em>In vitro</em> antiplasmodial activity and cytotoxicity of extracts and chromatographic fractions of twigs from <em>Pappea capensi</em>s EckI &... (Publications)
dried and then ground to fine powder. A solvent mixture of dichloromethane: methanol: water (1:0.5:0.5, v/v) was used to extract. The polar extract was separated from the non-polar. The organic extract
Comparative functional survival and equivalent annual cost of 3 long-lasting insecticidal net (LLIN) products in Tanzania: a randomised trial with... (Publications)
significantly different between the 3 net products (p = 0.001): 2.0 years (95% CI 1.7-2.3) for Olyset, 2.5 years (95% CI 2.2-2.8) for PermaNet 2.0 (hazard ratio [HR] 0.73 [95% CI 0.64-0.85], p = 0.001), and [...] between products as they aged. Equivalent annual cost varied between US$1.2 (95% CI $1.1-$1.4) and US$1.5 (95% CI $1.3-$1.7), assuming that each net was priced identically at US$3. The 2 longer-lived nets (PermaNet
Haematological consequences of acute uncomplicated <em>falciparum </em>malaria: a WorldWide Antimalarial Resistance Network pooled analysis of... (Publications)
America. The median haemoglobin concentration at presentation was 9.9 g/dL (range 5.0-19.7 g/dL) in Africa, 11.6 g/dL (range 5.0-20.0 g/dL) in Asia and 12.3 g/dL (range 6.9-17.9 g/dL) in South America. Moderately
Whole-genome sequence-informed MALDI-TOF MS diagnostics reveal importance of <em>Klebsiella oxytoca</em> group in invasive infections: a retrospective... (Publications)
cephalosporins than K. variicola isolates (odds ratio = 2.61, p = 0.003, 95% confidence interval [1.38,5.06]). K. oxytoca group isolates were found to be more likely associated with invasive infection to primary [...] sites than K. pneumoniae group isolates (odds ratio = 2.39, p = 0.0044, 95% confidence interval [1.05,5.53]). CONCLUSIONS: Currently misdiagnosed Klebsiella spp. can be distinguished using a ribosomal ma
The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient... (Publications)
co-blistered NFDC (97.9% [95% confidence interval (CI): 97.0-98.8%]) and FDC (98.1% [95% CI: 97.6%-98.5%]; P = 0.799), but significantly lower for the loose NFDC-25 (93.4% [95% CI: 91.9%-94.9%]), and loose [...] age, AQ dose, baseline parasitemia and region; treatment with loose NFDC-25 was associated with a 3.5-fold greater risk of recrudescence by day 28 (adjusted hazard ratio, AHR = 3.51 [95% CI: 2.02-6.12]
