Exposure to seasonal temperatures during the last month of gestation and the risk of preterm birth in Stockholm (Publications)
seasonal periods (heat in warm season, cold in cold season). The risk of preterm birth increased by 4%-5% when the mean temperature reached the 75th percentile (moderate heat) four weeks earlier (reference:
Synthesis and <em>in vitro</em> testing of antimalarial activity of non-natural-type neocryptolepines: structure-activity relationship study of 2,11-... (Publications)
synthesis and in vitro anti-malarial evaluations of certain C2 or C8 and C11-disubstituted 6-methyl-5H-indolo[2,3-b]quinoline (neocryptolepine congener) derivatives. To attain higher activities, the st
Agreement between parents and adolescents on dental fluorosis: a population-based study (Publications)
7%, but in the District of Rafael Arruda, evidence of very mild and mild fluorosis was found in 32.5% of the subjects, and moderate and severe fluorosis was found in 28.7%. There was poor agreement between
<em>Plasmodium vivax </em>molecular diagnostics in community surveys: pitfalls and solutions (Publications)
area in Brazil, application of a mitochondrial DNA-based assay increased prevalence from 4.9 to 6.5%. The usefulness of molecular tests in malaria epidemiological studies is widely recognized, especially
Recent investigations of artemether, a novel agent for the prevention of <em>Schistosomiasis japonica, mansoni </em>and <em>haematobia</em> (Publications)
indication of neurotoxicity following repeated high doses of artemether given fortnightly for up to 5 months. Randomized controlled clinical trials confirmed that artemether, orally administered at a dose
Factors associated with migration in individuals affected by leprosy, Maranhão, Brazil: an exploratory cross-sectional study (Publications)
diagnosed with leprosy and 391 from the clinically unapparent population. Of those with leprosy, 258 (65.5%) were birth migrants, 105 (26.6%) were past five-year migrants, and 43 (10.9%) were circular migrants
<em>In silico</em> prediction and experimental evaluation of furanoheliangolide sesquiterpene lactones as potent agents against <em>Trypanosoma brucei... (Publications)
exceptionally high level of in vitro activity. Four representative compounds of this type, goyazensolide, 4,5-dihydro-2' ,3' -epoxy-15-deoxygoyazensolide, budlein A and 4,15-isoatriplicolide tiglate, were therefore
Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule (Publications)
covalent inhibition is not preceded by the formation of a strong non-covalent complex. However, an up to 5-fold difference in inactivation rates among homologs hinted at structural or electrostatic differences
Epidemiological analysis of ozone and nitrogen impacts on vegetation - critical evaluation and recommendations (Publications)
model and conditions to be satisfied by the data; (4) selection of the relevant explanatory variables; (5) treatment of interactions and confounding factors; and (6) assessment of model validity.
European study of cohorts for air pollution effects (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/european-study-of-cohorts-for-air-pollution-effects
oxides. Airborne particulate matter will be characterized as inhalable (PM 10 ) and respirable (PM 2.5 ) particles as well as "soot" and elemental composition. Both NO and NO 2 will be measured in view of